ChemOffice在药理学教学中的应用实践  

Application of ChemOffice in the Teaching of Pharmacology

作　　者：段长飞 吴伟林 张素霞[1] 王少林[1] 吴聪明[1] 沈建忠[1] 王战辉[1] DUAN Chang-fei;WU Wei-lin;ZHANG Su-xia;WANG Shao-lin;WU Cong-ming;SHEN Jian-zhong;WANG Zhan-hui(College of Veterinary Medicine,China Agricultural University,Beijing 100193,China)

机构地区：[1]中国农业大学动物医学院,北京100193

出　　处：《广州化工》2023年第14期165-167,170,共4页GuangZhou Chemical Industry

基　　金：中国农业大学“教育教学改革系列研究项目”(KFKC202008、JC202008);万人计划-2019-王战辉(SQ2018RA20180005)。

摘　　要：药理学是医学学科中一门重要的专业基础课程,药物的药理作用与其分子结构和理化性质密切相关。ChemOffice是目前应用最广泛的化学结构及分子图形绘制软件,可绘制药物分子的二维和三维结构图,获得药物的各种理化参数,预测紫外、核磁和红外图谱等。介绍了ChemOffice在药理学中的基本应用,旨在引导学生自主绘制药物二维结构式或三维分子构象,加深对药物结构的认识;启发学生的创造性思维,进而提高药理学的教学质量。Pharmacology is a vital foundation course in Medicine specialty,the pharmacological effects of drugs are closely correlated to their molecular structures and physicochemical properties.ChemOffice is currently the most widely-used software for graphical drawing of chemical structures,which can be employed to draw two-and three-dimensional structures of drug molecules,obtain physical and chemical parameters,and predict ultraviolet,nuclear magnetic and infrared spectra.The base application of ChemOffice in pharmacology was introduced,aiming to guide students to draw the two-dimensional structural formulas or three-dimensional conformation of drugs independently,so as to deepen students'understanding of structures.Moreover,the introduction of ChemOffice could inspire out-of-box thinking,and then achieve the high-quality teaching of pharmacology.

关 键 词：药理学 ChemOffice 分子结构 应用实践 

分 类 号：R962[医药卫生—药理学]