胃癌免疫治疗的研究现状及进展  

The current research status and progress of immunotherapy for gastric cancer

作　　者：李娟(综述) 刘家仁(审校)[1] LI Juan;LIU Jiaren(Department of Clinical Laboratory,The 4th Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]哈尔滨医科大学附属第四医院检验科,哈尔滨150001

出　　处：《实用肿瘤学杂志》2023年第4期372-376,共5页Practical Oncology Journal

基　　金：国家自然科学基金(编号:82172580)。

摘　　要：目的胃癌作为一种具有高侵袭性和异质性的恶性肿瘤,是一个棘手的全球性健康问题,且目前胃癌的常规化疗存在耐药、易复发、不良反应严重等局限性。近年来人们对肿瘤相关基因及肿瘤发生发展机制进行了深入研究,研发出各类新型药物用于治疗胃癌,包括靶向药物、免疫治疗药等,并制定了不同的联合治疗策略,大大提高了胃癌患者的疗效。本文将围绕近几年胃癌免疫治疗的研究现状及进展进行综述。Gastric cancer,as a highly invasive and heterogeneous malignant tumor,is a thorny global health issue.Currently,conventional chemotherapy for gastric cancer has limitations such as drug resistance,susceptibility to recurrence,and severe adverse reaction.In recent years,many researchers have conducted many studies in-depth on tumors related to genes and the mechanisms of tumor occurrence and development,developed kinds of new drugs for gastric cancer treatment,including targeted drugs,immunotherapy drugs,etc.,and formulated different combination therapy strategies,which greatly improved the efficacy of gastric cancer patients.This article will review the research status and progress of immunotherapy for gastric cancer in recent years.

关 键 词：胃癌 免疫治疗 靶向药物 

分 类 号：R979.1[医药卫生—药品]