透析患者新型冠状病毒感染的临床研究现状  

An overview of clinical studies on SARS-CoV-2 infection in dialysis patients

作　　者：李作林[1] 潘明明[1] 王桂花[1] 尹清[1] 沈安然 杨琴 刘必成[1] Li Zuolin;Pan Mingming;Wang Guihua;Yin Qing;Shen Anran;Yang Qin;Liu Bicheng(Institute of Nephrology,Zhong Da Hospital,Southeast University School of Medicine,Nanjing 210009,China)

机构地区：[1]东南大学附属中大医院肾内科/东南大学肾脏病研究所,南京210009

出　　处：《中华肾脏病杂志》2023年第11期860-866,共7页Chinese Journal of Nephrology

基　　金：国家自然科学基金(82000648,82030024,82230022);江苏省自然科学基金(BK20200363);东南大学“优青”培育基金(2021ZDYYYQPY07);江苏省“双创”人才项目。

摘　　要：由严重急性呼吸综合征冠状病毒2型(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)引起的2019冠状病毒病(coronavirus disease 2019,COVID-19)的全球大流行给人类生命安全和经济生活造成了灾难性影响。临床研究表明,透析患者由于基础疾病多、疫苗接种率低,是SARS-CoV-2易感和高发人群,易发展为重症和导致死亡,更重要的是,透析人群往往临床症状不典型,部分甚至无症状,很难早期识别。本文通过对透析合并SARS-CoV-2感染患者的流行病学、临床特征、预后影响因素、疫苗接种以及治疗策略文献的总结分析,为临床诊治此类患者提供参考。The global pandemic of coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has had a catastrophic impact on human life and economic life.Due to the combination of multiple underlying diseases and low vaccination rates,dialysis patients are susceptible to SARS-CoV-2 infection and are likely to have more severe illness and even death.Moreover,dialysis patients with SARS-CoV-2 infection may initially present as asymptomatic or with mild symptoms,which makes it very difficult to identify severe patients at an early stage.Here,the epidemiology,clinical characteristics,risk factors for prognosis,vaccination and therapeutic strategies of dialysis patients with SARS-CoV-2 infection were summarized and analyzed,and it is hoped to provide a reference for the diagnosis and treatment of SARS-CoV-2 infection in this special group of patients.

关 键 词：新型冠状病毒肺炎 新型冠状病毒 透析 临床特征 危险因素 接种 治疗学 

分 类 号：R563.1[医药卫生—呼吸系统]