含异恶唑二铁配合物的合成、表征及电催化产氢性能和抗菌活性  

Synthesis,characterization,electrocatalytic properties,and antifungal activity of isoxazole-containing di-iron complexes

作　　者：刘旭锋[1,2] 李玉龙 刘幸海 LIU Xu-Feng;LI Yu-Long;LIU Xing-Hai(School of Materials and Chemical Engineering,Ningbo University of Technology,Ningbo,Zhejiang 315211,China;Zhejiang Institute of Tianjin University,Ningbo,Zhejiang 315201,China;College of Chemistry and Environmental Engineering,Key Laboratory of Green Chemistry of Sichuan Institutes of Higher Education,Sichuan University of Science&Engineering,Zigong,Sichuan 643000,China;College of Chemical Engineering,Zhejiang University of Technology,Hangzhou 310014,China)

机构地区：[1]宁波工程学院材料与化学工程学院,宁波315211 [2]天津大学浙江研究院,宁波315201 [3]四川轻化工大学化学与环境工程学院,绿色催化四川省高校重点实验室,自贡643000 [4]浙江工业大学化工学院,杭州310014

出　　处：《无机化学学报》2023年第12期2367-2376,共10页Chinese Journal of Inorganic Chemistry

基　　金：浙江省自然科学基金(No.LY19B020002);钒钛资源综合利用四川省重点实验室项目(No.2021FTSZ07);化学合成与污染控制四川省重点实验室项目(No.CSPC201904);四川省人社厅项目、自贡人才计划(2019);四川轻化工大学项目(No.202310622010,Y2023062);浙江三赢新材料有限公司项目(No.KYY-HX-20210140,KYY-HX-20200746)资助。

摘　　要：本文报道了4个含异恶唑基团的二铁配合物的制备及其结构表征。以含羟基二铁配合物[Fe_(2)(CO)_(6)(μ-SCH_(2)CH(CH_(2)OH)S)](1)与5-甲基异恶唑-4-羧酸为原料,经过酯化反应以高产率制备了配合物[Fe_(2)(CO)_(6)(μ-SCH_(2)CHCH_(2)OOC(5-C3HNOCH_(3))S)](2),再分别与三(对甲苯基)膦、三(4-氟苯基)膦或三(2-甲氧基苯基)膦反应,合成了3个含膦配合物[Fe_(2)(CO)5(L)(μ-SCH_(2)CHCH_(2)OOC(5-C3HNOCH_(3))S)],其中L=P(4-C_(6)H_(4)CH_(3))3(3)、P(4-C_(6)H_(4)F)3(4)、P(2-C_(6)H_(4)OCH_(3))_(3)(5)。使用元素分析、谱学和X射线晶体学对新配合物的结构进行了表征。电化学性质研究表明这些配合物可以催化醋酸中的质子还原产生氢气。其中,2拥有最低的过电位而4拥有最高的催化效率。此外,该类配合物还具有一定的抗菌活性。In this paper,four di-iron complexes with an isoxazole moiety were synthesized and characterized.The reaction of a hydroxy-containing di-iron complex[Fe_(2)(CO)_(6)(μ-SCH_(2)CH(CH_(2)OH)S)](1)with 5-methylisoxazole-4-carboxylic acid gave an ester product,named[Fe_(2)(CO)_(6)(μ-SCH_(2)CHCH_(2)OOC(5-C_(3)HNOCH_(3))S)](2)in very good yield.The phosphine-bearing analogues,which are named[Fe_(2)(CO)5(L)(μ-SCH_(2)CHCH_(2)OOC(5-C_(3)HNOCH_(3))S)]where L=P(4-C_(6)H_(4)CH_(3))3(3),P(4-C_(6)H_(4)F)3(4),P(2-C_(6)H_(4)OCH_(3))3(5),were prepared by the reactions of complex 2 with a mono-phosphine ligand tri(p-tolyl)phosphine,tris(4-fluorophenyl)phosphine or tris(2-methoxyphenyl)phosphine.Complex-es 2-5 have been identified by elemental analyses,spectroscopies,and X-ray crystallography.The electrochemical properties were probed by cyclic voltammetry,which shows that these complexes can catalyze the production of dihydrogen with acetic acid as a proton source.2 had the lowest overpotential and 4 had the highest catalytic effi-ciency.Moreover,we have investigated the antifungal activity of these new complexes.CCDC:2118524,2;2118526,4;2118527,5.

关 键 词：二铁配合物 异恶唑 X射线晶体学 电化学 抗菌活性 

分 类 号：O614.81[理学—无机化学]