前庭性偏头痛治疗药物选择  

Drug selection for the treatment of vestibular migraine

作　　者：吴百华[1] 施苗(综述) 董铭[1] 冯加纯(审校)[1] WU Baihua;SHI Miao;DONG Ming(Department of Neurology and Center of Neuroscience,The First Hospital of Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学第一医院神经内科和神经科学中心,吉林长春130021

出　　处：《中风与神经疾病杂志》2023年第11期1012-1016,F0003,共6页Journal of Apoplexy and Nervous Diseases

摘　　要：前庭性偏头痛(VM)是一种伴有头痛的发作性眩晕,临床上较为常见,其病理生理机制尚不完全清楚。VM临床表现多种多样,与良性阵发性位置性眩晕(BPPV)及梅尼埃病(MD)等外周眩晕疾病有相似或重叠表现,其神经系统检查通常无特殊表现。因此,没有客观诊断金标准,需进行排他性分析。目前因为VM的治疗缺少高等级证据级别的研究,以往的综述可能由于研究质量差和显著异质性而存在严重偏倚的风险。尽管VM治疗的总体证据基础质量较差,在这篇综述中,我们将以临床实用性为导向,对VM的各种治疗方案证据进行系统评估,同时,在此基础上提出治疗建议,希望对临床医生治疗VM患者有所帮助。Vestibular migraine(VM)is a type of paroxysmal vertigo with headaches.The condition is very common in clinical practice,but its pathophysiological mechanism is not fully understood.The clinical manifestations of VM vary greatly and are similar to or overlap with peripheral vertigo diseases such as benign paroxysmal positional vertigo(BPPV)and Meniere's disease(MD),and the neurological examinations of VM usually have no special findings.Therefore,there is no objective gold standard for diagnosis,and exclusive diagnoses are required.Due to the lack of high-level evidencebased studies on the treatment of VM,previous reviews may have been at serious risk of bias due to poor study quality and significant heterogeneity.Despite the poor quality of the overall evidence base for VM treatment,we have systematically performed a clinical practicability-oriented evaluation in this review on the evidence for various treatment options for VM.At the same time,we make treatment recommendations based on this evaluation,hoping to help clinicians in treating patients with VM.

关 键 词：前庭性偏头痛 急性期治疗 预防性治疗 

分 类 号：R764.3[医药卫生—耳鼻咽喉科] R747.2[医药卫生—临床医学]