水通道蛋白在热射病致中枢神经系统损伤中作用的研究进展  

Advance in the study of the role of aquaporins in the central nervous system damage caused by heat stroke

作　　者：李鑫[1] 马丽贞 孙莹[1] 汪茜[1] 宋青[3] LI Xin;MA Lizhen;SUN Ying;WANG Qian;SONG Qing(Department of Emergency,Third Medical Center of Chinese PLA General Hospital,Beijing 100039,China;Institute of Radiation Medicine,Academy of Military Medical Sciences,Academy of Military Sciences,Beijing 100850,China;Department of Critical Care Medicine,First Medical Center of Chinese PLA General Hospital,Beijing 100853,China)

机构地区：[1]解放军总医院第三医学中心急诊医学科,北京100039 [2]军事科学院军事医学研究院辐射医学研究所,北京100850 [3]解放军总医院第一医学中心重症医学科,北京100853

出　　处：《军事医学》2023年第10期793-797,共5页Military Medical Sciences

基　　金：军事医学创新工程专项(18CXZ024,18CXZ019)。

摘　　要：中枢神经系统损伤是热射病(HS)的典型特征之一,具有进展迅速、病死率高、致残率高的特点。水通道蛋白(AQP)在中枢神经系统广泛分布,在正常生命活动及多种疾病中发挥关键的调控作用。该文综述了AQP在HS所致中枢神经系统损伤中作用的研究进展,为提高对HS的认识、进一步探究其防治方法提供参考。The central nervous system(CNS)injury is one of the typical performances of heat stroke(HS),which is characterized by rapid progression,high mortality and high disability rates.Aquaporin(AQP)is widely distributed in the CNS and plays a key regulatory role in normal life activities and a variety of diseases.This article reviews the research progress in roles of AQP in CNS injury caused by HS so as to advance our understanding of HS and provide data for prevention and treatment of this disease.

关 键 词：热射病 水通道蛋白 中枢神经系统 

分 类 号：R594.12[医药卫生—内科学]