O型血与非O型血对急性下肢深静脉血栓形成患者预后的影响  

The influence of type-O blood and non-type-O blood on the prognosis of patients with acute lower extremity deep venous thrombosis

作　　者：郑国学 雍熙 李冈栉[1] 陈开[2] ZHENG Guoxue;YONG Xi;LI Gangzhi;CHEN Kai(Department of Cardiovascular Surgery,Suining Municipal Central Hospital,Hospital,Suining,Sichuan Province 629000,China)

机构地区：[1]遂宁市中心医院心血管外科,四川遂宁629000 [2]川北医学院附属医院血管外科

出　　处：《介入放射学杂志》2023年第11期1101-1105,共5页Journal of Interventional Radiology

摘　　要：目的 探讨血型与急性下肢深静脉血栓形成(DVT)预后的相关性。方法 回顾性分析2017年1月至2019年6月经川北医学院附属医院血管外科收治的急性下肢DVT患者的临床数据及1年期随访资料。按血型分成O型血组和非O型血组,对比两组患者住院期间患肢消肿率、血栓清除率、尿激酶用量、溶栓时间、住院时间、并发症发生率及出院后1年血栓复发率、血栓形成后综合征(PTS)发生率及Villalta评分,评估血型对DVT预后的影响。单因素和多因素logistic回归分析发生PTS的危险因素。结果 非O型血组DVT患者的PTS发生率、Villalta评分和治疗后的静脉通畅度得分均较O型血组高,且差异有统计学意义(P<0.05)。而患肢消肿率、血栓清除率、住院时间、并发症发生率等差异无统计学意义(P>0.05)。logistic回归分析结果显示,O型或非O血型(OR=4.337)、治疗后D-二聚体水平(OR=1.116)、合并肿瘤(OR=6.679)、治疗方式(OR=0.230)、血栓清除率(OR=0.900)和血栓复发(OR=97.628)是急性下肢DVT患者1年内发生PTS的独立危险因素。结论 非O型血是急性下肢DVT患者发生PTS的独立危险因素,在治疗急性下肢DVT患者时,应考虑到血型对预后的影响,从而实施个体化的最优治疗。Objective To investigate the correlation between blood types and prognosis of patients with acute lower extremity deep venous thrombosis(DVT).Methods The clinical data and one-year follow-up materials of patients with acute lower extremity DVT,who were admited to the Affiliated Hospital of North Sichuan Medical College of China between January 2017 and June 2019,were retrospectively analyzed.According to the blood type,the patients were divided into type-O blood group and non-type-O blood group.The detumescence rate of the affected limb,the thrombus clearance rate,the urokinase dosage,the thrombolysis time,the hospitalization days,the incidence of complications,and the one-year recurrence rate of thrombosis after discharge,the incidence of post-thrombotic syndrome(PTS),and the Villalta score were used to evaluate the effect of blood type on the prognosis of acute lower extremity DVT.Univariate analysis and multivariate regression analysis were used to analyze the risk factors for the occurrence of PTS.Results The incidence of PTS,Villalta score and postoperative venous patency score in the non-type-O blood group were higher than those in the type-0 blood group,and the differences were statistically significant(P<0.05).No statistically significant differences in the detumescence rate of the affected limb,the thrombus clearance rate,the hospitalization days and the incidence of complications existed between the two groups(P>0.05).Logistic regression analysis showed that type-0 blood or non-type-0 blood(OR=4.337),postoperative D-dimer level(OR=1.116),coexisting tumor(OR=6.679),treatment regimen(OR=0.230),thrombus clearance rate(OR=0.900),and thrombus recurrence(OR=97.628)were the independent risk factors for the occurrence of PTS within one year after treatment.Conclusion The non-type-O blood is an independent risk factor for PTS in patients with acute lower extremity DVT.Therefore,when treating patients with acute lower extremity DVT,the effect of blood type on the patient's prognosis should be taken into considera

关 键 词：血型 下肢深静脉血栓形成 血栓形成后综合征 预后 

分 类 号：R543.6[医药卫生—心血管疾病]