慢性乙型肝炎中医药免疫调控治疗的理论与实践  

Theory and practice of immunoregulatory therapy with traditional Chinese medicine for chronic hepatitis B

作　　者：李晓斌 刘博文 李峰[1] 苏晓鹏 胡世平 LI Xiaobin;LIU Bowen;LI Feng;SU Xiaopeng;HU Shiping(Beijing University of Chinese Medicine,Beijing 100029,China;Shenzhen Hospital Affiliated to Beijing University of Chinese Medicine,Shenzhen,Guangdong 518172,China)

机构地区：[1]北京中医药大学,北京100029 [2]北京中医药大学深圳医院,广东深圳518172

出　　处：《临床肝胆病杂志》2023年第12期2908-2913,共6页Journal of Clinical Hepatology

基　　金：国家自然科学基金面上项目(81973733);深圳市科技计划项目(JCYJ20220530172812028);深圳市龙岗医疗卫生科技创新计划(LGKCYLWS2021000015);深圳市龙岗区医疗卫生技术攻关项目(LGKCYLWS2022006)。

摘　　要：慢性乙型肝炎(CHB)仍为威胁人类健康的传染病之一,目前CHB的治疗以核苷(酸)类似物及干扰素为主,无法达到功能性治愈。CHB的发生发展与宿主免疫功能的失调密切相关,因此调节宿主免疫成为治疗CHB的关键环节。近年来研究表明中医药可通过调节宿主的免疫功能起到治疗CHB的作用,本文介绍了中医理论与免疫的关系,对CHB中医药免疫调控治疗的理论基础及相关研究进行概述以期为中西医结合治疗CHB提供思路。Chronic hepatitis B(CHB)is still a malignant infectious disease that seriously threatens human health,and currently nucleos(t)ide analogues and interferon are the main treatment methods for CHB,but they cannot achieve functional cure.The development and progression of CHB are closely associated with immune function dysregulation in the host,and therefore,regulating host immunity has become a key link in the treatment of CHB.Recent studies have shown that traditional Chinese medicine exerts a therapeutic effect on CHB by regulating host immune function.This article introduces the relationship between traditional Chinese medicine theory and immunity and summarizes the theoretical basis and related studies for traditional Chinese medicine in the immune regulation of CHB,in order to provide new ideas for integrated traditional Chinese and Western medicine therapy for CHB.

关 键 词：乙型肝炎 慢性 中医药疗法 免疫疗法 

分 类 号：R259[医药卫生—中西医结合]