EB病毒感染与消化系统疾病相关性的研究进展  

Research Progress in Correlation between Epstein-Barr Virus Infection and Gastrointestinal Diseases

作　　者：王茂生 郝菁华 许洪伟 WANG Maosheng;HAO Jinghua;XU Hongwei(Department of Gastroenterology,Provincial Hospital of Shandong First Medical University,Jinan 250021,China)

机构地区：[1]山东第一医科大学附属省立医院消化内科,济南250021

出　　处：《医学综述》2023年第22期5007-5011,共5页Medical Recapitulate

摘　　要：EB病毒(EBV)是淋巴细胞潜隐病毒家族的双链DNA病毒,具有传染性,传播途径主要包括接吻、分享食物或咳嗽等,其主要临床表现为发热、颈部和腋窝等部位淋巴结肿大以及扁桃体肿大等。EBV原发性感染通常无症状且可自愈,其严重程度与宿主免疫系统相关,在炎性肠病、慢性活动性EBV感染性肠炎等消化系统疾病的发生发展中发挥关键性作用。因此,深入研究EBV与消化系统疾病的相关性,可以为相关疾病的治疗提供新思路。Epstein-Barr virus(EBV)is a double stranded DNA virus of the lymphocytic latent virus family,which is infectious and mainly transmitted through kissing,sharing food or coughing.Its main clinical manifestations are fever,swollen lymph nodes in the neck,armpit and enlarged tonsils.Primary infection with EBV is usually asymptomatic and self-healing,and its severity is related to the host′s immune system.It plays a crucial role in the occurrence and development of digestive system diseases such as inflammatory bowel disease and chronic active EBV infectious enteritis.Therefore,in-depth studies on the correlation between EBV and digestive system diseases can provide new ideas for the treatment of related diseases.

关 键 词：消化系统疾病 EB病毒 炎性肠病 慢性活动性EB病毒感染 恶性肿瘤 

分 类 号：R373.1[医药卫生—病原生物学]