宫腔粘连致病因素研究现状  

Current Research Status of Pathogenic Factors for Intrauterine Adhesions

作　　者：史军艳 曾庆松[1] 易村犍[1] 易清华[1] SHI Junyan;ZENG Qingsong;YI Cunjian;YI Qinghua(Department of Obstetrics and Gynecology,the First Affiliated Hospital of Yangtze University,Jingzhou 434000,China)

机构地区：[1]长江大学附属第一医院妇产科,湖北荆州434000

出　　处：《医学综述》2023年第22期5032-5035,共4页Medical Recapitulate

摘　　要：宫腔粘连(IUA)是一种妇科常见的危害女性正常生育功能且预后不佳的宫腔疾病,严重影响女性身心健康。虽然目前IUA患者的预后已有所改善,但关于IUA的预防仍处于探索阶段。IUA致病因素复杂,常见的危险因素主要为与宫腔有创操作相关的医源性子宫内膜损伤,宫腔感染、子宫内膜血流低灌注、阴道微生物菌群均可促进IUA的发生发展。此外,与微RNA、长链非编码RNA相关的部分潜在因素也可诱发IUA。因此,早期识别诱发IUA的致病因素并有针对性地制订相关预防策略,可减少IUA的发生。Intrauterine adhesions(IUA)are a common gynecological disease that endangers women′s normal reproductive function and has a poor prognosis,seriously affecting women′s physical and mental health.Although the prognosis of patients with IUA has improved,the prevention of IUA is still in the exploratory stage.The pathogenic factors of IUA are complex,and the common risk factors are mainly iatrogenic endometrial damage related to invasive uterine procedures,while uterine infection,low endometrial blood flow perfusion,and vaginal microbiota can all promote the occurrence and development of IUA.In addition,some potential factors related to microRNAs and long non-coding RNAs can also induce IUA.Therefore,early identification of pathogenic factors that induce IUA and targeted development of relevant prevention strategies can reduce the occurrence of IUA.

关 键 词：宫腔粘连 致病因素 医源性子宫内膜损伤 

分 类 号：R711.74[医药卫生—妇产科学]