创伤性凝血病的研究进展  

Research of trauma-induced coagulopathy

作　　者：古力努尔·哈力木拉提 左蕾[1] GULINUR Halimulati;ZUO Lei(Department of Critical Care Medicine,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,China)

机构地区：[1]新疆医科大学第一附属医院重症医学科,830000

出　　处：《中国实用医药》2023年第22期161-164,共4页China Practical Medicine

摘　　要：创伤性凝血病(TIC)是指由创伤引起的以机体凝血与纤溶系统失衡、出血及血栓形成高风险为特点的凝血障碍性疾病。TIC发展的早期,通常会出现低凝状态,导致失控性出血,与患者早期死亡有关;而晚期TIC的特点是高凝状态,与静脉血栓栓塞和多器官衰竭相关。对于临床医师而言,TIC的病理生理机制异常复杂,导致早期失控性出血和晚期多器官功能衰竭的出现,这是一项极具挑战性的任务。通过对国内外相关文献资料的深入研究,探究TIC的发病机制,以期为早期诊断和治疗提供方向,从而降低早期死亡和晚期并发症的发生率,改善患者的预后。Traumatic-induced coagulopathy(TIC)is a kind of coagulation disorder characterized by imbalance of coagulation and fibrinolysis system,high risk of bleeding and thrombosis.In the early stages of TIC,there is usually a hypocoagulable state,which leads to uncontrolled bleeding and is associated with early death;whereas late TIC is characterized by high coagulation,which is associated with venous thromboembolism and multiple organ failure.The pathophysiological mechanism of TIC is complex.The early uncontrolled bleeding and the late multiple organ failure are severe challenges for clinicians.Through the in-depth study of relevant literature at home and abroad,the purpose of this study was to further understand the mechanism of TIC,so as to provide direction for early diagnosis and treatment,thus reducing early death and late complications,and improving the prognosis of patients.

关 键 词：创伤 凝血 影响因素 诊断 治疗 

分 类 号：R641[医药卫生—外科学]