血脂四项、肝功能、肾功能联合检验在2型糖尿病患者中的应用价值  

Application Value of Combined Test of Four-Item Blood Lipids,Liver Function and Renal Function in Patients with Type 2 Diabetes

作　　者：宋德慧 曹丽娜[2] 李毅[3] Song Dehui;Cao Lina;Li Yi(Beijing Fengtai Rehabilitation Hospital,Beijing 100079,China;Beijing Puren Hospital,Beijing 100062,China;Changping District Hospital of Integrated Traditional Chinese and Western Medicine,Beijing 102208,China)

机构地区：[1]北京市丰台康复医院,北京100079 [2]北京市普仁医院,北京100062 [3]北京市昌平区中西医结合医院,北京102208

出　　处：《中国社区医师》2023年第32期91-93,共3页Chinese Community Doctors

摘　　要：目的:探讨血脂四项、肝功能、肾功能联合检验在2型糖尿病患者中的应用价值。方法:选取2022年1—12月北京市丰台康复医院收治的2型糖尿病患者110例作为观察组,选取同院接受体检的健康人110例作为对照组。两组均进行血脂四项、肝功能和肾功能检查,比较两组各指标水平。结果:观察组空腹血糖、餐后2 h血糖水平高于对照组,差异有统计学意义(P<0.001)。观察组高密度脂蛋白胆固醇(HDL-C)水平低于对照组,低密度脂蛋白、总胆固醇、甘油三酯水平高于对照组,差异有统计学意义(P<0.001)。观察组总胆红素、白蛋白、直接胆红素、天门冬氨酸氨基转移酶、丙氨酸氨基转移酶、γ-谷氨酰转移酶、尿素氮、胱抑素、肌酐、尿酸水平高于对照组,差异有统计学意义(P<0.001)。Pearson相关分析显示,血脂四项、肝功能、肾功能指标中,HDL-C与空腹血糖水平呈负相关,其余指标均与空腹血糖水平呈正相关,差异有统计学意义(P<0.001)。结论:2型糖尿病患者的血脂四项、肝功能、肾功能水平与健康人存在差异,同时血脂四项、肝功能、肾功能水平与空腹血糖存在相关性,能够反映2型糖尿病患者血脂代谢及肝肾功能损伤程度。Objective:To investigate the application value of the combined test of four-item blood lipids,liver function and renal function in patients with type 2 diabetes.Methods:A total of 110 patients with type 2 diabetes treated in Beijing Fengtai Rehabilitation Hospital from January 2022 to December 2022 were selected as the observation group,and 110 healthy people who underwent physical examination in the same hospital were selected as the control group.Both groups were tested for four-item blood lipids,liver function and renal function.The levels of each index were compared between the two groups.Results:The levels of fasting blood glucose and 2 h postprandial blood glucose in the observation group were higher than those in the control group,with statistically significant differences(P<0.001).The levels of high density lipoprotein cholesterol(HDL-C)in the observation group were lower than those in the control group,and the levels of low density lipoprotein,total cholesterol and triglyceride in the observation group were higher than those in the control group,with statistically significant differences(P<0.001).The levels of total bilirubin,albumin,direct bilirubin,aspartate aminotransferase,alanine aminotransferase,gamma-glutamyltransferase,urea nitrogen,cystatin,creatinine,and uric acid in the observation group were higher than those in the control group,and the difference was statistically significant(P<0.001).Pearson correlation analysis showed that among the four-item blood lipids,liver function and renal function,HDL-C was negatively correlated with fasting blood glucose level,while the other indexes were positively correlated with fasting blood glucose level,with statistically significant differences(P<0.001).Conclusion:The levels of four-item blood lipids,liver function and renal function of type 2 diabetes patients are different from those of healthy people,and the levels of four-item blood lipids,liver function and renal function are correlated with fasting blood glucose,which can reflect the level of lipid m

关 键 词：血脂四项 肝功能 肾功能 2型糖尿病 

分 类 号：R587.1[医药卫生—内分泌]