凝血四项、血栓三项及D-二聚体在妊娠期高血压疾病与妊娠期糖尿病中的临床应用价值  

Clinical application value of blood clotting 4,thrombus 3 and D-dimer in gestational hypertension disease and gestational diabetes mellitus

作　　者：黄昊川 江长绿 江文力[1] 付小娟[1] Huang Haochuan;Jiang Changlv;Jiang Wenli;Fu Xiaojuan(Department of Clinical Laboratory,Huadu District People's Hospital,Guangzhou 510800,China)

机构地区：[1]广州市花都区人民医院检验科,广东广州510800

出　　处：《实用妇科内分泌电子杂志》2023年第24期96-98,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探究对妊娠期高血压疾病与妊娠期糖尿病患者采用凝血四项、血栓三项及D-二聚体(D-D)检验的临床价值。方法选取19例妊娠期糖尿病患者为观察组,17例妊娠期高血压疾病患者为研究组;另选取同期50例正常妊娠孕妇为参照组。三组均进行凝血四项、血栓三项及D-D检查,比较其检查结果。结果三组的凝血四项指标比较,差异无统计学意义(P>0.05)。与参照组比较,研究组纤维蛋白降解产物(FDP)、D-D指标明显降低,纤溶酶原(PLG)指标明显升高,观察组抗凝血酶(AT)、PLG、D-D指标明显升高(P<0.05);与观察组比较,研究组PLG明显升高,FDP、AT、D-D指标明显降低(P<0.05)。结论妊娠期糖尿病与妊娠期高血压疾病患者的相关指标较正常孕妇有所差异,具有明显的特异性,可以作为临床诊断标准。Objective To explore the clinical value of four coagulation tests,three thrombus tests and D-dimer(D-D)tests in patients with gestational hypertension and gestational diabetes.Methods 19 patients with gestational diabetes were selected as the observation group and 17 patients with gestational hypertension were selected as the study group.Another 50 normal pregnant women in the same period were selected as the reference group.All the three groups underwent four coagulation tests,three thrombus tests and D-D tests,and the Results were compared.Results There was no significant difference in four coagulation indexes among the three groups(P>0.05).Compared with the reference group,the indexes of fibrin degradation product(FDP)and D-D in research group were significantly decreased,plasminogen(PLG)indexes were significantly increased,and the indexes of antithrombin(AT),PLG and D-D in observation group were significantly increased(P<0.05).Compared with the observation group,PLG in the study group was significantly increased,while FDP,AT and D-D indexes were significantly decreased(P<0.05).Conclusion The relevant indexes of gestational diabetes mellitus and gestational hypertension are different from those of normal pregnant women,and have obvious specificity,which can be used as clinical diagnostic criteria.

关 键 词：妊娠期高血压疾病 妊娠期糖尿病 凝血四项 血栓三项 D-二聚体 

分 类 号：R714.246[医药卫生—妇产科学] R714.256[医药卫生—临床医学]