经尿道前列腺切除术治疗前列腺增生合并糖尿病的临床研究  

Clinical study of transurethral resection of prostate in treating prostatic hyperplasia complicated with diabetes mellitus

作　　者：师冠云 季广华 吕鑫 胡恩平[1] SHI Guanyun;JI Guanghua;LYU Xin;HU Enping(Department of Urology,Taizhou Municipal Hospital,Taizhou 318000,Zhejiang,China)

机构地区：[1]台州市立医院泌尿外科,浙江台州318000

出　　处：《中国现代医生》2023年第34期41-43,117,共4页China Modern Doctor

摘　　要：目的探究经尿道前列腺切除术不同术式治疗良性前列腺增生(benign prostatic hyperplasia,BPH)合并糖尿病的临床效果。方法选取2021年1月至12月台州市立医院收治的94例BPH合并2型糖尿病患者,根据随机数字表法将其分为观察组和对照组,每组各47例。对照组患者采用经尿道前列腺汽化电切术,观察组患者采用经尿道前列腺等离子电切术。比较两组患者的血糖、神经生长因子(nerve growth factor,NGF)、尿动力学指标和并发症情况。结果术中,观察组患者的血糖显著低于对照组(P<0.05)。观察组患者的NGF阳性细胞率显著低于对照组(P<0.05)。术后1个月,观察组患者的最大尿流率、膀胱顺应性均显著高于对照组,残余尿量显著低于对照组(P<0.05)。术后1个月内,观察组患者的并发症发生率显著低于对照组(P<0.05)。结论经尿道前列腺等离子电切术治疗BPH合并糖尿病患者可减轻手术对血糖的影响,改善逼尿肌功能及尿动力学,提升治疗效果的同时降低并发症发生率。Objective To explore the clinical effects of different types of transurethral resection of prostate in the treatment of benign prostatic hyperplasia(BPH)complicated with diabetes mellitus.Methods Ninety-four patients with BPH complicated with type 2 diabetes mellitus admitted to Taizhou Municipal Hospital from January to December 2021 were randomly divided into control group and observation group,with 47 cases in each group.The control group underwent transurethral vaporization resection of prostate,and the observation group underwent transurethral plasmakinetic resection of prostate.The blood sugar,nerve growth factor(NGF),urodynamic indexes and complications of two groups were compared.Results During the operation,the blood sugar in observation group was significantly lower than that in control group(P<0.05).The rate of NGF positive cells in observation group was significantly lower than that in control group(P<0.05).One month after operation,the maximum urine flow rate and bladder compliance in observation group were significantly higher than those in control group,and residual urine volume was significantly lower than that in control group(P<0.05).Within one month after operation,the incidence of complications in observation group was significantly lower than that in control group(P<0.05).Conclusion Transurethral plasmakinetic resection of prostate for BPH patients complicated with diabetes mellitus can reduce the influence of operation on blood sugar,improve detrusor function and urodynamics,improve the therapeutic effect and reduce the incidence of complications.

关 键 词：经尿道前列腺切除术 前列腺增生 糖尿病 治疗效果 安全性 

分 类 号：R697.3[医药卫生—泌尿科学] R587.1[医药卫生—外科学]