列线图预测T1-2期乳腺癌腋窝淋巴转移负荷的研究  

Nomograms for Predicting Axillary Node Metastatic Burden in T1-2 Breast Cancer

作　　者：赵杭菲 姚劲草 王立平[2] 范林音[2] 徐栋[2] Zhao Hangfei;Yao Jincao;Wang Liping;Fan Linyin;Xu Dong(Zhejiang Chinese Medical University,Hangzhou 310053,China;Zhejiang Cancer Hospital,Institute of Basic Medicine and Cancer(IBMC),Chinese Academy of Sciences,Hangzhou 310022,China)

机构地区：[1]浙江中医药大学,杭州市310053 [2]浙江省肿瘤医院,中国科学院基础医学与肿瘤研究所,杭州市310022

出　　处：《中国超声医学杂志》2023年第11期1224-1226,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的探讨基于T1-2期乳腺癌超声特征构建的列线图评估腋窝淋巴转移负荷的价值。方法回顾性分析407例经病理证实T1-2期原发性乳腺癌的超声征象,分为腋窝淋巴转移低负荷和高负荷组,对两组进行单因素及多因素分析后构建列线图,并评估模型效能。结果边缘、腋窝淋巴结、病灶分期T1-2是预测同侧腋窝淋巴高转移负荷的独立危险因素。基于这3个变量构建列线图,AUC达0.802,校准曲线及Hosmer-Lemeshow(H-L)表明了列线图预测能力较好。结论列线图预测T1-2期乳腺癌腋窝淋巴转移负荷能为临床医师提供参考。Objective To the value of nomograms constructed on the basis of ultrasound features of T1-2 breast cancer to assess axillary node metastatic burden.Methods The ultrasound signs of 407 patients with pathologically confirmed T1-2 breast cancer were retrospectively analyzed.They were divided into low and high nodal burden groups and a nomogram was constructed after univariate and multifactorial analyses for both groups,and assess the efficacy of the model.Results Irregular edge,positive nodes and T2 were independent risk factors for predicting high nodal burden in ipsilateral axillary nodes.Based on the three variables the nomogram was drawn,the area under the curve(AUC)was 0.802.The calibration plot and Hosmer-Lemeshow(H-L)test show the good predictive ability of the nomogram.Conclusions Normograms for predicting axillary lymph node metastatic burden in stage T1-2 breast cancer canbea reference for clinicians.

关 键 词：腋窝淋巴结 乳腺癌 列线图 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]