胸腔积液生化检测增设ADA与CEA项目对胸水性质鉴别诊断的价值  

The Value of Adding ADA and CEA Items in the Biochemical Detection of Pleural Effusion to the Differential Diagnosis of the Nature of Pleural Effusion

作　　者：胡斌 李子玉 刘润宇 Hu Bin;Li Zi-yu;Liu Run-yu(Department of Clinical Laboratory,Nanyang First People's Hospital,Nanyang 473000,Henan Province,China)

机构地区：[1]南阳市第一人民医院检验科,河南南阳473000

出　　处：《罕少疾病杂志》2023年第12期52-53,共2页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨胸腔积液生化检测增设测胸腔积液腺苷脱氨酶(ADA)与胸腔积液癌胚抗原(CEA)项目对胸腔积液性质进行鉴别诊断的应用价值。方法选择我院收治的胸腔积液患者90例进行观察,纳入时间:2019年8月-2021年8月,根据患者病情差异划分为结核性胸腔积液(A组,n=28)、恶性胸腔积液(B组,n=32)以及肺炎旁胸腔积液(C组,n=30),采用化学酶法检测患者胸腔积液ADA以及CEA含量,并进行记录。结果组间ADA在胸腔积液中的表达水平高于血清,且A组最高,C组最低,组间对比差异显著(P<0.05);CEA在胸腔积液中的表达水平高于血清,且C组最高,B组最低,组间对比差异显著(P<0.05);三组ADA以及CEA结果显示,A组胸腔积液ADA含量更高(P<0.05)。C组胸腔积液CEA含量更高(P<0.05)。结论针对患者的胸腔积液进行生化检测,并在其中增设ADA以及CEA两个项目,能够对患者胸腔积液的性质进行有效鉴别,并有助于临床医师进行疾病诊断,临床应用价值相对较高,可进行推广。Objective To explore the application value of the additional measurement of pleural effusion adenosine deaminase(ADA)and pleural effusion carcinoembryonic antigen(CEA)in the differential diagnosis of the nature of pleural effusion.Methods 90 patients with pleural effusion admitted to our hospital were selected for observation from August 2019 to August 2021.They were divided into tuberculous pleural effusion(Group A,n=28),malignant pleural effusion(Group B,n=32),and parapneumonic pleural effusion(Group C,n=30)based on the patient's condition.The ADA and CEA levels in the pleural effusion were measured using chemical enzyme method and recorded.Results The expression level of ADA in pleural effusion between groups was higher than that in serum,and Group A had the highest expression level,while Group C had the lowest expression level.The difference between groups was significant(P<0.05);The expression level of CEA in pleural effusion is higher than that in serum,and Group C has the highest expression level,while Group B has the lowest expression level,with significant differences between groups(P<0.05);The results of three sets of ADA and CEA showed that the ADA content in pleural effusion in group A was higher(P<0.05).The CEA content in pleural effusion in Group C was higher(P<0.05).Conclusion The biochemical detection of patients'pleural effusion,and the addition of two items of ADA and CEA,can effectively distinguish the nature of patients'pleural effusion,and help clinicians to diagnose diseases.The clinical application value is relatively high.High,can be promoted.

关 键 词：胸腔积液 胸水腺苷脱氨酶 胸水癌胚抗原 生化检测 鉴别诊断 

分 类 号：R561[医药卫生—呼吸系统]