中医体质类型与变应性鼻炎相关性的Meta分析  

META ANALYSIS OF THE CORRELATION BETWEEN TCM CONSTITUTION TYPE AND ALLERGIC RHINITIS

作　　者：田蒙珂 谢红卫[2] TIAN Mengke;XIE Hongwei(University of Birmingham,Birmingham B152TT;College of Public Health,Nanhua University,Hengyang 421001,China)

机构地区：[1]伯明翰大学医学与牙医学院,伯明翰B152TT [2]南华大学公共卫生学院,湖南衡阳421001

出　　处：《疾病监测与控制》2023年第4期258-262,共5页Journal of Diseases Monitor and Control

摘　　要：目的 基于文献检索对中医体质与变应性鼻炎相关性的数据进行Meta分析,以期为临床实践中变应性鼻炎的防治提供有效循证医学依据。方法 通过中国知网、PubMed等数据库筛选文献,使用AHRQ横断面研究质量评估量表,以Stata 12.0行Meta分析,再进行异质性分析。结果(1)研究共检索到文献266篇,最终纳入文献11篇,共3 848例变应性鼻炎样本。(2)根据Meta分析结果,变应性鼻炎患者的体质以气虚质[95%CI=0.35(0.23,0.48),P <0.01]、阳虚质[95%CI=0.25(0.17,0.32),P <0.01]、特禀质[95%CI=0.24(0.14,0.35),P <0.01]居多,其中气虚质最为常见。结论现有证据表明,气虚质、阳虚质和特禀质是变应性鼻炎患者的主要中医体质类型,气虚、阳虚及遗传特异体质可能是变应性鼻炎患病的危险因素。这个结论还需要更多的高质量、多中心、大样本的RCT实验来证实。Objective Based on literature search,meta analysis was conducted on the data of the correlation between allergic rhinitis and traditional Chinese medicine constitution,in order to provide effective evidence-based medical basis for the prevention and treatment of allergic rhinitis in clinical practice.Methods Literatures were screened through PubMed,CNKI and other databases.AHRQ cross-sectional study quality assessment scale,Stata12.0 were used for meta-analysis,and then heterogeneity analysis was performed.Results(1)A total of 266 articles were retrieved,and 11 articles were included in the final analysis,with 3848 samples from allergic rhinitis patients.(2)According to the results of meta-analysis,the constitution of allergic patients consisted of Qi-deficiency quality [95% CI=0.35(0.23,0.48),P <0.01],Yang-deficiency quality [95% CI=0.25(0.17,0.32),P <0.01],inherited specialties quality [95%CI=0.24(0.14,0.35),P <0.01],among which Qi-deficiency was the most common.Conclusions Existing evidence shows that Qi-deficiency,Yang-deficiency and inherited specialties deficiency are the main TCM constitution types of patients with allergic rhinitis,and qi-deficiency,Yang-deficiency and genetic specific constitution may be the risk factors for allergic rhinitis.However,this conclusion needs more high-quality,multi-center,large-sample RCT experiments to confirm.

关 键 词：变应性鼻炎 中医体质辨识 META分析 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]