氢氧混合气对肩袖损伤术后早期的影响  

Effect of hydrogen-oxygen mixture inhalation on early consequences of arthroscopic repair of rotator cuff tear

作　　者：陈印忠 郭威 郭秀程 贾庆卫 晁毓菡 尹宗生[2] CHEN Yinzhong;GUO Wei;GUO Xiu-cheng;JIA Qing-wei;CHAO Yu-han;YIN Zong-sheng(The Second Affiliated Hospital,Shandong First Medical University,Taian 271000,China;The First Affiliated Hospital of Anhui Medical University,Hefei 230022,China;Taishan College,Taian 271000,China)

机构地区：[1]山东第一医科大学第二附属医院,山东泰安271000 [2]安徽医科大学第一附属医院,安徽合肥230022 [3]泰山学院,山东泰安271000

出　　处：《中国矫形外科杂志》2023年第22期2091-2094,共4页Orthopedic Journal of China

基　　金：山东省老年医学会科技攻关计划项目(编号:LKJGG2021W093);山东省医药卫生发展计划项目(编号:2018WS123);泰安市科技发展计划项目(编号:2022NS220);山东省社会科学普及应用项目(编号:2021-SKZC-56)。

摘　　要：[目的]探讨氢氧混合气对肩袖损伤术后早期肩关节功能的影响。[方法]回顾性分析2020年2月—2021年10月60例行单侧肩关节镜下肩袖修补术的患者。依据术前医患沟通结果,30例术后吸入氢氧混合气(氢氧组),30例术后吸入纯氧气(纯氧组)。比较两组临床结果与检验资料。[结果]患者均顺利完成手术,两组手术时间、插管30 min后平均动脉压及心率变化差异无统计学意义(P>0.05)。所有患者均完成12周随访,随时间推移,术后两组VAS评分、UCLA和Constant-Murley评分均显著改善(P<0.05)。术前两组上述评分的差异均无统计学意义(P>0.05),术后12周,氢氧组VAS评分[(1.7±0.6)vs(2.2±0.7),P<0.05]、UCLA[(29.1±0.8)vs(28.3±1.5),P<0.05]以及Constant-Murley评分[(93.7±2.1)vs(91.4±3.9),P<0.05]均显著优于纯氧组。检验方面,两组患者术后血清IL-6及TNF-a水平均显著降低(P<0.05)。术后12周,氢氧组的IL-6[(1.5±0.8)pg/ml vs(2.2±0.3)pg/ml,P=0.040]和TNF-α[(2.0±0.9)pg/ml vs(2.6±0.9)pg/ml,P=0.026]均显著低于纯氧组。[结论]术后吸入氢氧混合气可以缓解肩关节镜术后肩关节痛疼,改善肩关节功能。[Objective]To explore the effect of hydrogen-oxygen mixture inhalation on early consequences of arthroscopic repair of ro-tator cuff tear.[Methods]A retrospective study was performed on 60 patients who underwent unilateral arthroscopic rotator cuff repair fromFebruary 2020 to October 2021.According to the preoperative doctor-patient communication,30 patients were inhaled hydrogen and oxy-gen mixture(the HOM group),while other 30 patients were inhaled pure oxygen(the PO group).The clinical and blood test data of the twogroups were compared.[Results]All patients were operated on successfully,without significant differences in the operation time,mean arte-rial pressure and heart rate 30min after intubation between the two groups(P>0.05).As all patients were followed up for 12-weeks,theVAS score for pain,Constant-Murley and UCLA scores in both groups were significantly improved over time(P<0.05).Although there wasno statistical significance in the above scores between the two groups before surgery(P>0.05),the HOM group proved significantly superiorto the PO group 12 weeks after surgery in terms of VAS score[(1.7±0.6)vs(2.2±0.7),P<0.05],UCLA[(29.1±0.8)vs(28.3±1.5),P<0.05]andConstant-Murley score[(93.7±2.1)vs(91.4±3.9),P<0.05].Regarding blood test,the levels of serum IL-6 and TNF-a in both groups weresignificantly decreased after surgery(P<0.05).The HOM group was significantly lower than the PO group in terms of IL-6[(1.5±0.8)pg/mlvs(2.2±0.3)pg/ml,P=0.040]and TNF-alpha[(2.0±0.9)pg/ml vs(2.6±0.9)pg/ml,P=0.026]12 weeks postoperatively.[Conclusion]Inhala-tion of hydrogen and oxygen mixture does relieve pain and improve function after arthroscopic repair of rotator cuff tear.

关 键 词：肩袖损伤 关节镜术 炎性因子 氢氧混合气 

分 类 号：R687[医药卫生—骨科学]