儿童心室预激性心肌病研究进展  

Advances in ventricular pre-excitation-induced cardiomyopathy in children

作　　者：柯思思(综述) 张勇(审校)[2] Ke Sisi;Zhang Yong(School of Medicine,Wuhan University of Science and Technology,Wuhan 430065,China;Department of Cardiovascular Medicine,Wuhan Children′s Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430019,China)

机构地区：[1]武汉科技大学医学院,430065 [2]华中科技大学同济医学院附属武汉儿童医院心血管内科,430019

出　　处：《国际儿科学杂志》2023年第11期728-731,共4页International Journal of Pediatrics

基　　金：湖北省自然科学基金(2019CFB783)。

摘　　要：心室预激性心肌病临床上起病隐匿, 多数无明显临床症状, 往往在症状出现时已有心脏扩大、心功能不全等。与心室预激相关的旁道是引起心室预激性心肌病的重要病因, 及时阻断旁道可有效逆转部分甚至全部心功能。药物治疗、导管消融治疗均被应用于心室预激性心肌病的治疗。随着三维标测技术的发展以及治疗手段的成熟, 儿童心室预激性心肌病的手术成功率高、并发症低, 且在低龄、低体重患儿方面不断取得进展。冷冻消融是传统射频消融的有益补充, 为心室预激性心肌病提供了一种安全有效的消融方法。该文就儿童心室预激性心肌病研究进展作一综述。While most patients with pre-excitation-induced cardiomyopathy have insidious onset and no obvious clinical symptoms in the early stage,cardiac enlargement and insufficiency often manifest when symptoms appear.The accessory pathway is the primary etiology of pre-excitation-induced cardiomyopathy,and its blockade could result in partial or complete resolution of the left ventricular ejection fraction.Both drug therapy and catheter ablation have been used to treat pre-excitation-induced cardiomyopathy.And the outcome of catheter ablation in pediatric patients has demonstrated a higher rate of success,less incidence of complications and especially notable advancements in the treatment of young children with low body mass due to the development of three-dimensional electro-anatomic mapping technology and the progress in therapy.Moreover,cryoablation is a significant supplement to traditional radiofrequency ablation,which has provided a relatively safe and effective treatment method for pre-excitation-induced cardiomyopathy.This paper reviews the research progress of pre-excitation-induced cardiomyopathy in children.

关 键 词：儿童 心室预激 心肌病 导管消融 

分 类 号：R725.4[医药卫生—儿科]