老年创伤凝血功能异常与静脉系血栓风险相关性研究进展  

Research progress on the correlation between abnormal coagulation function and the risk of venous thrombosisin seniletrauma

作　　者：金禹辰 许永安[1,2,3,4] Jin Yuchen;Xu Yongan(Department of Emergency medicine,the Second Affiliated Hospital,School of Medicine&Institute of Emergency Medicine,Zhejiang University&Key Laboratory of The Diagnosis and Treatment of Severe Trauma and Burn of Zhejiang Province&Zhejiang Province Clinical Research Center for Emergency and Critical Care Medicine,Hangzhou 310009,China)

机构地区：[1]浙江大学医学院附属第二医院急诊医学科 [2]浙江大学急救医学研究所 [3]浙江省严重创伤与烧伤诊治重点实验室 [4]浙江省急危重症临床医学研究中心,杭州310009

出　　处：《中华老年医学杂志》2023年第12期1511-1515,共5页Chinese Journal of Geriatrics

基　　金：国家自然科学基金项目(No.81372079,81201478);浙江省医药卫生科技计划资助(No.2016145610,2020KY577)。

摘　　要：老年创伤患者数量逐年增多,其发生创伤性凝血病(TIC)等各种凝血功能异常的风险较高,而创伤患者在治疗期间并发静脉系血栓(VTE)也同样常见,这都影响老年创伤患者的救治策略及预后。由于创伤性凝血功能紊乱的机制尚未完全阐明,TIC等创伤相关凝血功能紊乱和VTE形成之间的病理生理过程及相关性的研究较少。本文针对老年创伤凝血状态、TIC发病机制与治疗以及VTE的相关研究进行综述,为老年创伤血栓预防和治疗提供一定的依据。The number of elderly trauma patients is increasing each year,leading to a higher risk of various coagulation disorders such as traumatic coagulation disease(TIC).Additionally,venous thrombosis(VTE)is a common complication during treatment for trauma patients,further impacting the treatment strategy and prognosis of elderly trauma patients.However,the mechanism of traumatic coagulation disorder is not fully understood,and there is limited research on the pathophysiological process and correlation between TIC and VTE formation.This article reviewed relevant studies on the coagulation status,pathogenesis,and treatment of TIC and VTE in elderly trauma patients,providing a foundation for the prevention and treatment of thrombosis in this population.

关 键 词：创伤性凝血病 血栓 

分 类 号：R641[医药卫生—外科学]