2017-2022年云南省艾滋病高危人群人类免疫缺陷病毒新近感染监测结果分析  

Surveillance for human immunodeficiency virus infection in population at high risk for acquired immune deficiency syndrome in Yunnan,2017−2022

作　　者：张祖样 宋丽军[1] 肖民扬 王晓雯[1] 陈会超[1] 金晓媚[1] 李雪华[1] 付丽茹[1] 牛瑾[1] 罗红兵[1] Zhang Zuyang;Song Lijun;Xiao Minyang;Wang Xiaowen;Chen Huichao;Jin Xiaomei;Li Xuehua;Fu Liru;Niu Jin;Luo Hongbing(Yunnan Center for Disease Control and Prevention,Kunming 650034,Yunnan,China)

机构地区：[1]云南省疾病预防控制中心,云南昆明650034

出　　处：《疾病监测》2023年第11期1330-1333,共4页Disease Surveillance

基　　金：国家科技重大专项(No.2018ZX10715006-006)。

摘　　要：目的了解云南省女性商业性服务者和性病门诊男性就诊者人类免疫缺陷病毒(HIV)新近感染情况,为艾滋病防治策略制定和评估提供参考。方法采用连续横断面研究方法在艾滋病监测哨点开展女性商业性服务者和性病门诊男性就诊者中HIV新近感染监测,使用限制性抗原亲和力酶联免疫法(LAg法)对HIV抗体阳性样本进行新近感染检测,根据通用公式计算HIV新近感染率。结果2017—2022年云南省女性商业性服务者哨点共开展HIV检测64058人份,HIV阳性率为0.36%~0.89%,呈下降趋势(趋势χ^(2)=27.024,P<0.001);HIV新近感染率为0.05%~0.27%,无直线线性变化趋势(r=0.090,P=0.865)。性病门诊男性就诊者哨点共开展HIV检测31642人份,HIV阳性率为0.53%~1.00%,无直线线性变化趋势(趋势χ^(2)=3.076,P=0.079);HIV新近感染率为0.20%~0.31%,无直线线性变化趋势(r=-0.558,P=0.208)。结论云南省女性商业性服务者和性病门诊男性就诊者HIV感染率和新近感染率维持在相对较低水平,持续开展新近感染监测对艾滋病疫情研判具有重要意义。Objective To understand the infection status of human immunodeficiency virus(HIV)in female sex workers(FSWs)and male patients with sexually transmitted diseases(STDs)and influencing factors in Yunnan province during 2017−2022.Methods A cross-sectional study was used in HIV sentinel surveillance in FSWs and male STD patients,and HIV-positive samples were tested for recent infections by LAg–Avidity enzyme immunoassay.The recent HIV infection rate was calculated according to the recommended general formula.Results A total 64058 HIV tests were conducted in FSWs in sentinel surveillance in Yunnan during this period,and the HIV positive rate ranged from 0.36%to 0.89%,showing an overall downward trend(trendχ^(2)=27.024,P<0.001),and the recent HIV infection rate ranged from 0.05%to 0.27%,showing no obvious linear change trend(r=0.090,P=0.865).A total of 31642 HIV tests were conducted in male STD patients in sentinel STD clinics in Yunnan during this period,and the HIV positive rate ranged from 0.53%to 1.00%,showing no linear change trend(trendχ^(2)=3.076,P=0.079).And the recent HIV infection rate ranged from 0.20%to 0.31%,showing no linear change trend(r=−0.558,P=0.208).Conclusion The infection rate and recent infection rate of HIV remained low in FSWs and male STD patients in Yunnan.Continuous surveillance for recent infection of HIV is important for the assessment of acquired Immune deficiency syndrome epidemic in Yunnan.

关 键 词：女性商业性服务者 性病门诊 男性就诊者 人类免疫缺陷病毒 感染率 新近感染率 

分 类 号：R211[医药卫生—中医学] R512.9