阻塞性睡眠呼吸暂停致日间过度嗜睡患者多导睡眠监测特点分析  

Characteristics of Polysomnographic Sleep Monitoring(PSG)in Patients with Obstructive Sleep Apnea(OSA)Induced Daytime Excessive Sleepiness(EDS)

作　　者：惠培林[1] 范杰 马薇[1] 张尚丽 李渊[1] 谢宇平[1] HUI Peilin;FAN Jie;MA Wei;ZHANG Shangli;LI Yuan;XIE Yuping(Sleep Medicine Center,Gansu Provincial People′s Hospital/Gansu Provincial Sleep Clinical Medicine Research Center,Lanzhou 730000,China)

机构地区：[1]甘肃省人民医院睡眠医学中心/甘肃省睡眠临床医学研究中心,兰州730000

出　　处：《世界睡眠医学杂志》2023年第9期2215-2219,共5页World Journal of Sleep Medicine

基　　金：国家自然科学基金地区科学基金项目(81560228,82160267);甘肃省科技重点研发计划项目(21YF5FA020);甘肃省科技计划项目临床医学研究中心建设项目(20JR10RA437);甘肃省青年科技计划项目(21JR7RA637);2021年甘肃省卫生健康委科研计划项目(GSWSKY2021-005);2019甘肃省卫生行业科研计划书(GSWSKY-2019-88);甘肃省人民医院基金项目(18GSSY4-19,18GSSY4-20,2019-264)。

摘　　要：目的:探索阻塞性睡眠呼吸暂停(OSA)引起日间过度嗜睡(EDS)患者的多导睡眠监测(PSG)特点。方法:选取2021年8月至2022年8月甘肃省人民医院睡眠医学中心门诊或住院的OSA引起日间过度嗜睡患者(ESS量表≥12分)42例,年龄、性别匹配的OSA不伴有嗜睡(ESS量表<12分)患者46例,探索OSA引起EDS患者的夜间睡眠特点。结果:OSA伴EDS组和OSA不伴EDS组比较,AHI、夜间ASpO 2、总睡眠时间、睡眠效率、N1期睡眠占比、N2期睡眠占比差异均无统计学意义(均P>0.05)。夜间LSpO 2、睡眠潜伏时间、觉醒指数、N3期睡眠比、R期睡眠比占比差异均有统计学意义(均P<0.05)。结论:OSA伴EDS患者表现出不同于OSA不伴EDS患者的PSG特点,其夜间缺氧更严重、觉醒次数更多、深睡眠比例更低。Objective:To investigate the characteristics of polysomnography,PSG in patients with Excessive daytime sleepiness(EDS)caused by obstructive sleep apnea(OSA).Methods:Forty-two patients with obstructive sleep apnea(OSA)induced excessive daytime sleepiness(ESS≥12 points)were selected from the outpatients or inpatients of the Sleep Medicine Center of Gansu Provincial People′s Hospital between August 2021 and August 2022.Forty-six age-and sex-matched patients with OSA without drowsiness(ESS scale<12 points)were enrolled to explore the night sleep characteristics of OSA-induced EDS patients.Results:There were no significant differences in AHI,nocturnal ASpO 2,total sleep time,sleep efficiency,proportion of sleep in N1 phase and proportion of sleep in N2 phase between OSA group and OSA group without EDS(all P>0.05).There were statistically significant differences in LSpO 2 at night,latent sleep time,wake index,N3 sleep ratio and R sleep ratio(all P<0.05).Conclusion:The PSG characteristics of OSA patients with EDS were different from those of OSA patients without EDS,with more severe nighttime hypoxia,more awakenings,and lower proportion of deep sleep.

关 键 词：睡眠呼吸暂停 日间过度嗜睡 夜间睡眠特点 

分 类 号：R714.253[医药卫生—妇产科学] R338.63[医药卫生—临床医学]