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作 者:蔡华波[1] 王朝霞 CAI Hua-bo;WANG Zhao-xia(Shenzhen Children's Hospital,Shenzhen 518034,China)
出 处:《中国实用儿科杂志》2023年第12期893-895,共3页Chinese Journal of Practical Pediatrics
基 金:中华消化内镜创新发展专项(Z-2019-45-2001);福棠儿童医学发展研究中心资助项目(FTSCR-2021-04)。
摘 要:食管狭窄是儿童常见疾病之一,多为食管手术后继发的吻合口狭窄、腐蚀性物质损伤、先天性狭窄、胃食管反流引起的食管炎以及嗜酸性粒细胞性食管炎等良性狭窄。有多种方法治疗儿童食管狭窄,内镜直视下球囊扩张术较为安全而且有效,是首选的治疗方法。文章就儿童食管狭窄的球囊扩张术的术前准备及注意事项、并发症及治疗方法等方面加以阐述。除了内镜下球囊扩张治疗,辅以丝裂霉素-C局部治疗可改善腐蚀性食管狭窄的吞咽困难及减少扩张次数,辅以类固醇激素局部治疗有可能减少难治性食管狭窄。内镜下球囊扩张治疗后,随访患儿年龄别体重Z分数的增加提示了营养状况的改善,扩张间隔逐渐延长或1年内不再需要扩张可认为临床治疗成功。Esophageal stenosis is a prevalent condition in children,primarily resulting from anastomotic strictures,corrosive substance injuries,congenital anomalies,gastroesophageal reflux-induced esophagitis,and eosinophilic esophagitis.Although various treatment options are available for pediatric patients with oesophagal stenosis,endoscopic balloon dilatation remains a safe and effective therapeutic choice.This article reviews the preoperative preparation,precautions,complications and treatment of balloon dilatation for esophageal stenosis in children.Furthermore,local adjuvant mitomycin-C therapy can relieve dysphagia and reduce dilation frequency in caustic oesophagal stenosis.Local adjuvant steroid hormone therapy could potentially mitigate refractory oesophagal stenosis.After undergoing endoscopic balloon dilation treatment,the observed increase in weight-for-age Z-scores during follow-up indicates an improvement in nutritional status.Gradual extension of dilation intervals or cessation of further dilation within one year can indicate successful clinical treatment.
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