黄芪止嗽饮治疗儿童气阴两虚型过敏性咳嗽临床观察  

Efficacy observation of modified Huangqi Zhisou yin on children's allergic cough with syndrome of deficiency of both qi and yin

作　　者：袁洋[1] 李志武[1] 陈光明[1] 徐玲[1] 杨丽霞[1] 马海龙[1] 许璿 YUAN Yang;LI Zhi-wu;CHEN Guang-ming(Yancheng Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Traditional Chinese Medicine,Yancheng 224001,China)

机构地区：[1]南京中医药大学附属盐城中医院,盐城224001

出　　处：《山西中医》2023年第12期15-17,共3页Shanxi Journal of Traditional Chinese Medicine

基　　金：江苏省中医药科技发展计划项目(编号:YB2020078);江苏省盐城市医学科技发展计划项目(编号:YK2020037)。

摘　　要：目的:观察黄芪止嗽饮加减治疗儿童气阴两虚型过敏性咳嗽的临床疗效。方法:采用随机分组、平行对照的方法将气阴两虚型过敏性咳嗽患儿分为两组各40例。对照组予地氯雷他定干混悬剂口服治疗,治疗组予黄芪止嗽饮加减口服治疗,1周为1个疗程,治疗2个疗程后比较两组临床疗效及咳嗽缓解时间、咳嗽消失时间;并评价两组咳痰、流涕、咽痒、鼻痒、多汗、睡时打鼾等症状消失时间。结果:治疗组临床总有效率90.0%优于对照组的72.5%(P﹤0.05);治疗组咳嗽缓解时间及咳嗽消失时间明显优于对照组(P﹤0.05);治疗组的咳痰、流涕、咽痒、多汗等症状消失时间明显优于对照组(P﹤0.05);而治疗组鼻痒及睡时打鼾症状消失时间与对照组比较,差异无统计学意义(P﹥0.05)。结论:基于“护阳益阴”理论选用经验方黄芪止嗽饮加减辨证施治儿童气阴两虚型过敏性咳嗽有较好的临床疗效,可明显改善患者临床症状。Objective:To observe the clinical efficacy of modified Huangqi Zhisou yin on children's allergic cough with syndrome of deficiency of both qi and yin.Methods:80 cases of children patients with allergic cough with syndrome of deficiency of both qi and yin were divided into two groups by methods of randomized grouping and parallel control,40 cases in each group.The control group was treated with oral desloratadine for dry suspension,while the treatment group was treated with oral modified Huangqi Zhisou yin.One week was one course of treatment.After two courses of treatment,the clinical efficacy,cough relieving time and cough disappearing time were compared between two groups;the disappearing time of symptoms such as expectoration,runny nose,itching throat,itching nose,hyperhidrosis and snoring during sleep etc.were evaluated in two groups.Results:The clinical total effective rate of treatment group was 90.0%,which was better than 72.5%of control group(P﹤0.05).The cough relieving time and cough disappearing time of treatment group were significantly better than those of control group(P﹤0.05).The disappearing time of symptoms such as expectoration,runny nose,itching throat and hyperhidrosis etc.of treatment group was significantly better than that of control group(P﹤0.05).But the difference was not statistically significant compared disappearing time of symptom of itching nose and snoring during sleep between two groups(P﹥0.05).Conclusion:Based on the theory of"protecting yang and benefiting yin",the empirical formula of modified Huangqi Zhisou yin has better clinical efficacy on children's allergic cough with syndrome of deficiency of both qi and yin in syndrome differentiation and treatment,which can significantly improve the clinical symptoms of patients.

关 键 词：过敏性咳嗽 儿童 气阴两虚 黄芪止嗽饮 中医药疗法 

分 类 号：R256.11[医药卫生—中医内科学]