行气化滞方加减治疗乳腺增生症临床观察  

Efficacy observation of modified Xingqi Huazhi formula on cyclomastopathy

作　　者：王飞鸿 张银艳 钱江 廖枚 曾婷[1] 解银欣 朱春丽 杨钦文 WANG Fei-hong;ZHANG Yin-yan;QIAN Jiang(Hunan University of Traditional Chinese Medicine,Changsha 410208,China;不详)

机构地区：[1]湖南中医药大学,长沙410208 [2]重庆市垫江县中医院 [3]重庆医科大学

出　　处：《山西中医》2023年第12期21-24,共4页Shanxi Journal of Traditional Chinese Medicine

基　　金：重庆市科卫联合医学科研项目(编号:2022MSXM186)。

摘　　要：目的:观察行气化滞方治疗乳腺增生症的临床疗效及乳腺增生中医分型与血清因子的相关性。方法:选取乳腺增生症患者120例作为治疗组,按辨证分型分为3组,选取健康体检女性40例为对照组。治疗组予行气化滞方加减治疗,4周为1个疗程。结果:肝郁气滞组69例,总有效率为94.20%;痰瘀互结组23例,总有效率为91.30%;冲任失调组28例,总有效率为89.29%;各组间疗效比较差异无统计学意义(P﹥0.05)。治疗前,MDA水平:冲任失调组﹥痰瘀互结组﹥肝郁气滞组﹥对照组(P﹤0.05),SOD水平:肝郁气滞组﹥痰瘀互结组﹥冲任失调组﹥对照组(P﹤0.05),GSH-Px水平:肝郁气滞组﹥痰瘀互结组﹥对照组(P﹤0.05),冲任失调组与对照组比较无统计学差异(P﹥0.05),各证型组T-AOC水平均低于对照组(P﹤0.05),各证型组组间比较无统计学差异(P﹥0.05)。治疗后治疗组MDA水平低于治疗前,SOD、GSH-PX、T-AOC水平均高于治疗前,差异均有统计学意义(P﹤0.05)。结论:基于“治乳不离气”理论采用行气化滞方治疗乳腺增生症患者,能够有效减轻患者乳房疼痛,缩小乳房肿块。Objective:To observe the clinical efficacy of modified Xingqi Huazhi formula on cyclomastopathy and the correlativity between TCM typing and serum factors of breast hyperplasia.Methods:120 cases of patients with cyclomastopathy were selected as treatment group that was divided into 3 sub-groups by syndrome differentiation typing,and 40 cases of healthy physically examinated women were selected as control group.The treatment group was treated with modified Xingqi Huazhi formula,4 weeks as a course of treatment.Results:The total effective rate was 94.20%in the group of liver depression and qi stagnation with 69 cases,91.30%in the group of intermingled phlegm and blood stasis with 23 cases and 89.29%in the group of disharmony of Chong and Ren meridians with 28 cases,and the differences were not statistically significant compared the efficacy among groups(P﹥0.05).Before treatment:in MDA level,group of disharmony of Chong and Ren meridians﹥group of intermingled phlegm and blood stasis﹥group of liver depression and qi stagnation﹥control group(P﹤0.5);in SOD level,group of liver depression and qi stagnation﹥group of intermingled phlegm and blood stasis﹥group of disharmony of Chong and Ren meridians﹥control group(P﹤0.5);in GSH-Px level,group of liver depression and qi stagnation﹥group of intermingled phlegm and blood stasis﹥control group(P﹤0.05),the difference was not statistically significant compared group of disharmony of Chong and Ren meridians with control group(P﹥0.05).In T-AOC level,the group of each syndrome type was lower than the control group(P﹤0.05),and the difference was not statistically significant compared between two groups of different syndrome types(P﹥0.05).After treatment,MDA level of treatment group was lower than before treatment,while the levels of SOD,GSH-PX and T-AOC were higher than before treatment,and the differences were statistically significant(P﹤0.05).Conclusion:Based on the theory of"treating breast based on qi",the patients with cyclomastopathy are treated

关 键 词：乳腺增生症 治乳不离气 行气化滞方 中医药疗法 

分 类 号：R271.9[医药卫生—中西医结合]