大青龙汤研究进展  

Research progress of Daqinglong Decoction

作　　者：马启风 王炳然 张淼 陈晶 邱智东[1] 高红梅[1] MA Qifeng;WANG Bingran;ZHANG Miao;CHEN Jing;QIU Zhidong;GAO Hongmei(Changchun University of Chinese Medicine,Changchun 130117,China)

机构地区：[1]长春中医药大学,长春130117

出　　处：《吉林中医药》2023年第12期1493-1496,共4页Jilin Journal of Chinese Medicine

基　　金：中医药事业传承发展资金支持项目《重大疫情防治中药方剂储备库建设项目》(吉中医药发[2021]11号);2023年全国中药特色技术传承人才培训项目(T20234832005)。

摘　　要：大青龙汤始载于《伤寒论》,由麻黄、桂枝、甘草、苦杏仁、大枣、生姜、石膏7味中药组成,是医圣张仲景治疗外寒里热,表里俱实的一剂古方。现代研究表明,大青龙汤具有抗病毒、退热、抗炎的药理作用,化学成分研究发现,大青龙汤含有生物碱、苯丙素、黄酮、有机酸、三萜类等成分,临床应用大多通过加减或联合西药用于感冒、无汗症、哮喘、急性肾炎等疾病的治疗。现通过查阅相关文献,对大青龙汤的历史沿革、药理作用、化学成分及临床应用进行综述,以期为该方深入研究及合理应用提供参考。Daqinglong Decoction,first recorded in the Treatise on Cold Pathogenic Diseases,is composed of seven Chinese medicines.It is an ancient prescription by Zhang Zhongjing for treating the syndromes of external cold and internal heat,excess in both superficies and interior.Modern research shows that Daqinglong Decoction has the pharmacological effects of anti-virus,antipyretic and anti-inflammation,while chemical composition research shows that the formula contains alkaloids,phenylpropanoids,flavonoids,organic acids,triterpenes and other components,Clinically,it is mostly used to treat cold,anhidrosis,asthma,acute nephritis and other diseases by being flexibly modified or combining with western medicines.This paper reviews the historical evolution,pharmacological actions,chemical compositions and clinical application of Daqinglong Decoction by consulting relevant literature,with the view of providing reference for its further study and rational application.

关 键 词：大青龙汤 历史沿革 药理作用 化学成分 临床应用 

分 类 号：R289[医药卫生—方剂学]