针刺联合止吐药防治全麻术后恶心呕吐效果的Meta分析  

Meta-analysis of the effect of acupuncture combined with antiemetics on prevention and treatment of nausea and vomiting after general anesthesia

作　　者：司尚坤 刘慧 王法帅 张维亮[3] 张栋斌 苏帆[3] SI Shangkun;LIU Hui;WANG Fashuai;ZHANG Wei liang;ZHANG Dongbin;SU Fan(College of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine,Jinan 250014,China)

机构地区：[1]山东中医药大学中医学院,济南市250014 [2]山东中医药大学第一临床医学院,济南市250014 [3]山东中医药大学附属医院麻醉科

出　　处：《临床麻醉学杂志》2023年第11期1178-1184,共7页Journal of Clinical Anesthesiology

基　　金：山东省医学会临床科研资金-齐鲁专项(YXH2022ZX02103);济南市科技创新发展计划(202134068);济南市“新高校20条”科研带头人工作室项目(202228124)。

摘　　要：目的系统评价针刺(手针、电针)防治全麻术后恶心呕吐的效果。方法计算机检索Embase、PubMed、Cochrane、中国知网、维普、中国生物医学文献数据库、万方医学等数据库,纳入有关针刺联合止吐药防治全麻术后恶心、呕吐的随机对照试验(RCT),检索年限为建库至2022年9月,采用RevMan 5.3进行统计分析。结果共纳入15篇文献,患者1493例,其中止吐药组741例,针刺联合止吐药组752例。与止吐药组比较,针刺联合止吐药组术后恶心发生率明显降低(OR=0.43,95%CI 0.34~0.54,P<0.001),术后呕吐发生率明显降低(OR=0.55,95%CI 0.45~0.66,P<0.001)。结论与单用止吐药比较,采用针刺(手针、电针)联合止吐药患者术后恶心和呕吐的发生率更低。Objective To evaluate the effect of acupuncture(manual acupuncture,electroacupuncture)on prevention and treatment of nausea and vomiting after general anesthesia.Methods By searching CNKI,VIP,China Biomedical Literature Database,Wanfang Medical,Embase,PubMed,Cochrane Clinical Trial Registry,randomized controlled trial(RCT)on acupuncture combined with antiemetics for the prevention and treatment of nausea and vomiting after general anesthesia were performed.The retrieval period was from the establishment of the database to September 2022.RevMan 5.3 was used for statistical analysis.Results Fifteen studies involving 1493 patients were included.There were 741 patients in the antiemetic group and 752 patients in the acupuncture combined antiemetic group.The incidence of postoperative nausea in the acupuncture combined with antiemetics group was significantly lower than that in the simple antiemetics group(OR=0.43,95%CI 0.34-0.54,P<0.001).The incidence of postoperative vomiting in the acupuncture combined with antiemetics group was significantly lower than that in the simple antiemetics group(OR=0.55,95%CI 0.45-0.66,P<0.001).Conclusion The incidence of postoperative nausea and vomiting was lower in patients treated with acupuncture(manual acupuncture,electroacupuncture)combined with antiemetics than with antiemetics alone.

关 键 词：术后恶心呕吐 针刺 针灸疗法 止吐药 随机对照试验 META分析 

分 类 号：R246.2[医药卫生—针灸推拿学]