Bezold-Jarisch反射与临床麻醉  

Bezold-Jarisch reflex and clinical anesthesia

作　　者：傅润乔 FU Runqiao(Department of Anesthesiology,Airfoce Medical Center,Beijing 100142,China)

机构地区：[1]空军特色医学中心麻醉科,北京市100142

出　　处：《临床麻醉学杂志》2023年第11期1202-1206,共5页Journal of Clinical Anesthesiology

摘　　要：贝措尔德-雅里施反射(BJR)反射的概念经历了100多年,是由左心室无髓鞘迷走神经输入感受器被刺激(药物或机械性牵拉),通过迷走神经传入脑干孤束核整合后传到血管运动中枢,形成迷走神经输出增强,导致严重心动过缓、外周血管舒张、血压降低甚至心搏骤停,以心脏抑制为主的一种心血管抑制性反应。其在临床麻醉上直接应用的概念不多,关注度不够,以至于围术期一些突发的严重心动过缓、低血压、甚至心跳骤停在机理上分析存在缺位。The concept of the Bezold-Jarisch reflex(BJR)has experienced more than 100 years,which is that the left ventricular unmyelinated vagus nerve input receptors are stimulated by drugs or mechanical pull,the stimulation was then integrated by the vagus nerve afferent brain stem nucleus and transmitted to the vascular movement center to form vagal nerve output enhancement,leading to severe bradycardia,peripheral vasodatation,hypotension and even cardiac arrest,e.g,a cardiovascular inhibitory reaction.Although BJR is applied in clinical anesthesia,insufficient attention has been paid to it,resulting in absence of the mechanism analysis of related sudden severe bradycardia,hypotension,and even cardiac arrest in perioperative period.

关 键 词：贝措尔德-雅里施反射 临床麻醉 左心室 心脏抑制 防治 

分 类 号：R614[医药卫生—麻醉学]