静脉氯胺酮与硬膜外吗啡超前镇痛对胃切除术病人的作用  

Preemptive Analgesia by Intravenous Ketamine and Epidural Morphine in Gastrectomy

作　　者：黄宁[1] 杨光[1] 林鹰[1] 

机构地区：[1]哈尔滨医科大学第三临床医学院麻醉科,黑龙江哈尔滨150040

出　　处：《黑龙江医学》2002年第11期819-820,共2页Heilongjiang Medical Journal

摘　　要：目的　探讨静脉氯胺酮与硬膜外吗啡超前镇痛对胃切除术病人的作用。方法　ASAⅠ～Ⅱ级胃切除术病人 6 0例 ,随机分成 4组 ,第 1组 :静脉内注入氯胺酮 ;第 2组 :硬膜外注入吗啡 ;第 3组 :静脉氯胺酮与硬膜外吗啡联合注入 ;第 4组 :静脉与硬膜外分别注入盐水。分别测定术后 6、12、2 4、4 8h的视觉模拟评分、运动后痛觉评分及术后镇痛吗啡消耗量。结果　第 3组术后各时间点的视觉模拟评分、运动后痛觉评分及术后镇痛吗啡消耗量与其他各组相比均明显减少 (P <0 0 5 )。Objective To evaluate effect of preemptive analgesia by intravenous ketamine and epidural morphine in gastrectomy.Method Sixty gastrectomy patients ASA Ⅰ～Ⅱ were randomly divided into 4 groups.In group A preemptive analgesia by intravenous ketamine;In group B preemptive analgesia by epidural morphine;In group C preemptive analgesia combination by intravenous ketamine and epidural morphine;In group D intravenous water and epidural water.Visual analog scale,categoric pain evaluation,and cumulative morphine consumption were measured after operation 6,12,24 and 48 hours.Result:In group C visual analog scale,categoric pain evaluation,and cumulative morphine consumption were reduction significantly at every time point compared with the other 3 group(P<0 05).Conclusion There is a definitive effect of preemptive analgesia by intravenous ketamine and epidural morphine in gastrectomy.

关 键 词：静脉 氯胺酮 硬膜外吗啡 超前镇痛 胃切除术 

分 类 号：R656.6[医药卫生—外科学] R614.[医药卫生—临床医学]