低剂量联合低浓度对比剂在320排CT冠状动脉成像中的研究  

Study of Low Dose and Low Concentration Contrast Agent in 320-rowCoronary Computer Tomography Angiography

作　　者：鲍招弟 马壮飞 宋丹丹[1] 王超[1] 齐星亮[1] BAO Zhaodi;MA Zhuangfei;SONG Dandan;WANG Chao;QI Xingliang(Beijing Pinggu Hospital,Beijing 101200,P.R.China;Canon Medical System(China)Limited Company,Beijing 101200,P.R.China)

机构地区：[1]北京市平谷区医院,北京101200 [2]佳能医疗系统(中国)有限公司,北京101200

出　　处：《影像科学与光化学》2023年第6期283-289,共7页Imaging Science and Photochemistry

基　　金：北京市平谷区医院青年基金(Pgyyqn2021-02)。

摘　　要：探究低剂量联合低浓度对比剂在320排CT冠状动脉成像中的可行性。前瞻性收集接受CT冠状动脉成像的患者153例,其中A组49例,B组52例,C组52例。三组扫描的管电压分别为80 kV、100 kV和100 kV,对比剂浓度分别为300 mgI/mL、300 mgI/mL和350 mgI/mL。统计数据显示三组图像左前降支(LAD)中远段和左回旋支(LCX)远段的CT值差异无统计学意义(P>0.05),其余节段A组的CT值均高于B、C组(P<0.05);三组图像LAD中远段、LCX中远段、右冠状动脉(RCA)中远段噪声值(SD)差异无统计学意义(P>0.05);三组图像冠状动脉各节段的信噪比(SNR)、对比度噪声比(CNR)和主观评分差异均无统计学意义(P>0.05);A组的有效辐射剂量(ED)明显低于B组和C组,并且差异具有统计学意义(P<0.05)。综上所述,低剂量联合低浓度对比剂可以用于320排CT冠状动脉成像中,有利于减低X线辐射和高浓度对比剂对患者的危害。To explore the feasibility of low dose combined with low concentration contrast agent in 320-row coronary computer tomography(CT)angiography.153 patients who underwent coronary computer tomography angiography were prospectively collected.49 patients were included in group A,52 patients were included in group B,and 52 patients were included in group C.The tube voltage of three groups were 80 kV,100 kV and 100 kV,respectively.The concentration of contrast agent of three groups were 300 mgI/mL,300 mgI/mL and 350 mgI/mL,respectively.Statistical data are shown,there were no significant differences in the CT values of the middistal left anterior descending(LAD)and the distal left circumflex(LCX)of three groups(P>0.05),and the CT values of the other segments in group A were higher than those in group B and C(P<0.05).There were no significant differences in the noise values of the middistal LAD,LCX and right coronary artery(RCA)in the three groups ( P >0.05). There were no significant differences in signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and subjective scores among the three groups ( P >0.05). The radiation dose of group A was significantly lower than that of group B and group C ( P <0.05). In conclusion, low dose combined with low concentration contrast agent can be used in 320-row coronary CTA, which is conducive to reducing the harm of X-ray radiation and high concentration of contrast agent to patients.

关 键 词：CT冠状动脉成像 320排CT 低剂量 低浓度对比剂 

分 类 号：R816.2[医药卫生—放射医学]