改良mdt模式应用于高龄晚期非小细胞肺癌患者的研究  

Study of the application of modified MDT model on elderly patients with advanced non-small cell lung cancer

作　　者：李颖[1] LI Ying(Department of Respiratory Medicine,Jiujiang NO.1 People's Hospital,Jiangxi Province,Jiujiang332000,China)

机构地区：[1]江西省九江市第一人民医院呼吸内科,江西九江332000

出　　处：《中国当代医药》2023年第34期188-191,共4页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202211817)。

摘　　要：目的探究改良多学科协作(MDT)模式应用于高龄晚期非小细胞肺癌(NSCLC)患者的效果。方法选取2020年8月至2022年4月九江市第一人民医院呼吸内科的60例高龄NSCLC患者作为研究对象,采用随机数字表法分为试验组(30例)及对照组(30例)。两组患者均行化疗治疗,对照组患者采用普通MDT模式,试验组患者采用改良MDT模式。比较两组患者生存情况[总生存期(OS)、无疾病生存期(DFS)]及非预期住院次数、主观疗效。结果试验组OS、DFS均长于对照组,非预期住院次数少于对照组,差异有统计学意义(P<0.05)。试验组总有效率为80.00%,高于对照组的53.33%,差异有统计学意义(P<0.05)。结论改良MDT模式在高龄晚期NSCLC患者中应用能够有效延长生存时间,在一定程度上改善生存情况,减少非预期住院次数,提升主观疗效,值得推广应用。Objective To explore the effect of modified multi-disciplinary treatment(MDT)model in elderly patients with advanced non-small cell lung cancer(NSCLC).Methods A total of 60 elderly NSCLC patients in the Department of Respiratory Medicine of Jiujiang First People's Hospital from August 2020 to April 2022 were selected as the study objects,and they were divided into experimental group(30 cases)and control group(30 cases)by random number table method.Two groups of patients were treated with chemotherapy,the control group was treated with ordinary MDT mode,and the experimental group was treated with modified MDT mode.Survival situation(overall survival[OS],disease-free survival[DFS]),unexpected hospitalization and subjective efficacy were compared between the two groups.Results The OS and DFS of experimental group were longer than those of control group,and the number of unexpected hospitalization was less than that of control group,the differences were statistically significant(P<0.05).The total effective rate of experimental group was 80.00%,which was higher than that of control group(53.33%),and the difference was statistically significant(P<0.05).Conclusion The application of modified MDT mode in elderly patients with advanced NSCLC can effectively prolong the survival time,improve the survival situation to a certain extent,reduce the number of unexpected hospitalizations,and improve the subjective efficacy,which is worthy of promotion and application.

关 键 词：晚期非小细胞肺癌 高龄患者 改良多学科协作模式 传统多学科诊疗模式 生存期 

分 类 号：R473.73[医药卫生—护理学]