双功能二氧化硫替代物在合成磺酰类化合物中的研究进展  

Recent Advances of Bifunctional Sulfur Dioxide Surrogates in Synthesis of Sulfonyl Compounds

作　　者：吴宇恒 颜岩[1] 寮渭巍 Wu Yuheng;Yan Yan;Liao Weiwei(College of Chemistry,Jilin University,Changchun 130012)

机构地区：[1]吉林大学化学学院,长春130012

出　　处：《有机化学》2023年第11期3713-3727,共15页Chinese Journal of Organic Chemistry

摘　　要：近年来通过二氧化硫插入合成磺酰类化合物的合成方法受到了研究者的关注.多种二氧化硫替代物参与的磺酰化反应被相继报道,并成功用于多种磺酰类化合物如砜、磺酰氟和磺酰胺等的合成.其中部分二氧化硫替代物展现出了双功能的作用——既作为二氧化硫源用于构建磺酰基,又作为体系中的还原剂.具有还原性的二氧化硫阴离子自由基在这些反应中起到了关键作用,提高了磺酰化反应的效率和原子经济性.重点介绍了近年来这类双功能二氧化硫替代物在磺酰类化合物合成中的研究进展.The synthesis of sulfonyl compounds via sulfur dioxide insertion has received considerable attention from chemists recently.Various sulfonyl compounds such as sulfones,sulfonyl fluorides and sulfonamides have been prepared through the fixation of sulfur dioxide by employing sulfur dioxide surrogates.In particular,some of sulfur dioxide surrogates display a bifunctional role:not only serving as a source of sulfur dioxide,but also acting as a reducing agent in the desired sulfonylation reactions.The reductive sulfur dioxide anion radical plays a key role in these transformations,and the efficiency and atomic economy of these reactions have been enhanced greatly.This review highlights the recent advances of such bifunctional sulfur dioxide surrogates involved sulfonylation transformations.

关 键 词：SO_(2)插入 SO_(2)阴离子自由基 双功能试剂 磺酰化 

分 类 号：O623.8[理学—有机化学]