手性烯丙基硅烷的催化对映选择性合成  

Catalytic Enantioselective Preparation of Chiral Allylsilanes

作　　者：匡鑫 丁昌华 吴奕晨 王鹏[2,3,4] Kuang Xin;Ding Changhua;Wu Yichen;Wang Peng(College of Science,Shanghai University,Shanghai 201900;State Key Laboratory of Organometallic Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032;CAS Key Laboratory of Energy Regulation Materials,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032;School of Chemistry and Material Sciences,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,Hangzhou 310024)

机构地区：[1]上海大学理学院,上海201900 [2]中国科学院上海有机化学研究所、金属有机化学国家重点实验室,上海200032 [3]中国科学院上海有机化学研究所、中国科学院能量调控材料重点实验室,上海200032 [4]中国科学院大学杭州高等研究院、化学与材料科学学院,杭州310024

出　　处：《有机化学》2023年第10期3367-3387,共21页Chinese Journal of Organic Chemistry

基　　金：国家重点研发计划(2021YFA1500200);国家自然科学基金(22101291);国家自然科学基金(22171277);国家自然科学基金(21821002);上海“启明星”(20QA1411400)。

摘　　要：手性烯丙基硅烷作为多功能试剂被广泛应用于不对称合成中,因而,发展高效的方法构建该类化合物受到了大家的广泛关注.伴随着不对称催化领域的快速发展,催化不对称合成手性烯丙基硅烷已经取得了重要的进展.详细总结了手性烯丙基硅烷催化不对称合成的进展,并展示了其在有机合成中的应用.Chiral allylsilanes,a versatile linchpin,are widely used in the area of asymmetric synthesis.Therefore,the development of efficient methodologies for the preparation of the enantioenriched allylsilanes has attracted great attention.Significant advances have been made in the catalytic enantioselective preparation of chiral allylsilanes by virtue of the rapid developments in asymmetric catalysis.The advances in the construction of chiral allylsilanes and their synthetic applications are summarized.

关 键 词：手性烯丙基硅烷 不对称合成 催化合成 

分 类 号：O627.41[理学—有机化学]