铜催化烯醇硅醚与芳基亚磺酸钠合成β-酮砜的研究  

Copper-Catalyzed Synthesis ofβ-Keto Sulfones from Enol Silyl Ether and Sodium Arylsulfinates

作　　者：许力 吕兰兰 王香善 Xu Li;LüLanlan;Wang Xiangshan(School of Chemistry and Materials Science,Jiangsu Normal University,Xuzhou,Jiangsu 221116)

机构地区：[1]江苏师范大学化学与材料科学学院,江苏徐州221116

出　　处：《有机化学》2023年第10期3644-3651,共8页Chinese Journal of Organic Chemistry

基　　金：江苏省高校面上项目(No.22KJD150003);2023年度江苏师范大学实验室研究课题(No.L2023YB08)资助项目。

摘　　要：β-酮砜是一类重要的含硫化合物和有机合成中间体,被广泛应用于天然产物及许多重要有机化合物的构筑.开发了一种溴化铜催化烯醇硅醚与芳基亚磺酸钠快速合成β-酮砜的方法,具有操作简单、条件温和和反应时间短等优点.β-Keto sulfones are an important group of sulfur-containing compounds and intermediates for organic synthesis,which are widely used in the construction of natural products and various important organic compounds.A method for the rapid synthesis ofβ-keto sulfones catalyzed by copper bromide from enol silyl ether and sodium arylsulfinates is developed,which has the advantages of simple operation,mild conditions and short reaction time.

关 键 词：β-酮砜 铜催化 烯醇硅醚 芳基亚磺酸钠 

分 类 号：O621.251[理学—有机化学]