山东省三城市有异性性行为MSM的艾滋病病毒暴露前预防用药意愿及相关因素  

Willingness and related factors of using HIV pre-exposure prophylaxis among MSM with heterosexual behavior in three cities of Shandong Province

作　　者：杨晓楠 韩磊[2] 黄鹏翔[2] 李金海[2] 于海英[2] 王传琪 李亚君 王霖 郝连正[2] 王国永[2] 马伟 YANG Xiaonan;HAN Lei;HUANG Pengxiang;LI Jinhai;YU Haiying;WANG Chuanqi;LI Yajun;WANG Lin;HAO Lianzheng;WANG Guoyong;MA Wei(School of Public Health,Cheeloo College of Medicine,Shandong University,Jinan 250012,Shandong,China;Shandong Center for Disease Control and Prevention,Jinan 250014,Shandong,China)

机构地区：[1]山东大学齐鲁医学院公共卫生学院,济南250012 [2]山东省疾病预防控制中心,济南250014

出　　处：《中国艾滋病性病》2023年第11期1184-1187,共4页Chinese Journal of Aids & STD

基　　金：山东省自然科学基金项目(ZR2022MH160);山东省医药卫生科技发展计划项目(202112050690,202012051340)。

摘　　要：目的分析山东省三城市有异性性行为的MSM对HIV的PrEP用药意愿及相关影响因素。方法利用滚雪球的抽样方法,在山东省3个市通过面对面问卷调查收集研究对象的人口学特征、行为学特征和PrEP用药意愿等信息,以是否有PrEP的用药意愿作为因变量,采用χ2检验、多因素Logistic回归分析其影响因素。结果共纳入416名有异性性行为MSM,38.7%(161人)的研究对象有PrEP用药意愿。多因素Logistic回归结果显示,婚姻状况为在婚或同居(OR=2.172,95%CI:1.124~4.197)、双性恋者(OR=1.703,95%CI:1.035~2.804)是PrEP用药意愿的促进因素,而年龄在25~35岁(OR=0.293,95%CI:0.119~0.723)、36~45岁(OR=0.209,95%CI:0.070~0.623)、有2个以上同性临时性伴(OR=0.440,95%CI:0.252~0.770)以及进行过HIV抗体检测(OR=0.459,95%CI:0.277~0.761)是PrEP用药意愿的阻碍因素。结论山东省三城市有异性性行为的MSM对PrEP用药意愿较低,应加强针对该人群的宣传教育,提高对PrEP的用药意愿。Objective To analyze the willingness to use HIV pre-exposure prophylaxis(PrEP)and its related influencing factors among men who have sex with men(MSM)with heterosexual behavior in three cities of Shandong Province.Methods In terms of snowball sampling,the demographic characteristics,behavioral characteristics and the willingness to use PrEP were collected by face-to-face questionnaire survey in three cities in Shandong Province.Willingness to use PrEP was taken as the dependent variable,and the influencing factors were analyzed by chi-squared test and multiple logistic regression.Results A total of 416 participants were included,and 38.7%(161/416)were willing to use PrEP.Multiple logistic regression showed that the marriage or cohabitation(OR=2.172,95%CI:1.124-4.197),bisexuality(OR=1.703,95%CI:1.035-2.804)were the promoters of willingness to use PrEP,while at the age of 25 to 35 years(OR=0.293,95%CI:0.119-0.723),36 to 45 years old(OR=0.209,95%CI:0.070-0.623),having 2 or more temporary sexual partners(OR=0.440,95%CI:0.252-0.770),and having previous HIV antibody testing(OR=0.459,95%CI:0.277-0.761)were barriers of willingness to use PrEP.Conclusions MSM with heterosexual behavior in three cities of Shandong Province has a lower willingness to use PrEP.It is necessary to strengthen publicity and education targeting at this population,so as to improve their willingness to use PrEP.

关 键 词：男男性行为者 异性性行为 暴露前预防 用药意愿 

分 类 号：R373.9[医药卫生—病原生物学]