2011-2020年广西梅毒血清学检测室间质评结果分析  

External quality assessment for syphilis serological test in Guangxi from 2011 to 2020

作　　者：韦江平 韦晓宁 陈媚 朱邦勇 WEI Jiangping;WEI Xiaoning;CHEN Mei;ZHU Bangyong(Department of Clinical Laboratory,Dermatology Institute of Guangxi Zhuang Autonomous Region,Nanning 530007,Gaungxi,China;Department of Obstetrics and Gynecology,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi,China)

机构地区：[1]广西壮族自治区皮肤病防治研究所检验科,南宁530007 [2]广西医科大学第一附属医院妇产科,南宁530021

出　　处：《中国艾滋病性病》2023年第11期1240-1244,共5页Chinese Journal of Aids & STD

摘　　要：目的了解广西相关医疗机构实验室梅毒血清学检验质量水平,进一步加强梅毒实验室质量控制和管理。方法每家参评实验室发放5份质评样本,分别进行非特异性梅毒螺旋体抗体血清学定性、定量试验和特异性梅毒螺旋体抗体血清学试验,收集检测结果;并对2011―2020年,各年参评单位数、仪器设备、质评结果进行分析。结果2011-2020年参加广西室间质量评价活动的医疗机构数由48增加到406家,参评单位陆续开展了梅毒非特异性及特异性抗体血清学试验;仪器设备逐渐完备。室间质评合格率逐年上升(χ^(2)=64.50,P<0.01),2016-2020五年合格率均超过97%,2011-2020年参评单位梅毒非特异性抗体血清学定性试验的符合率均较高,除2018年(68.0%)外,其余各年定性试验符合率均高于90%;而定量试验符合率10年中波动较大,分别为79.2%、56.7%、74.0%、72.2%、58.6%、74.4%、90.1%、60.3%、89.8%、71.2%。梅毒特异性抗体血清学试验符合率较为平稳,除2013、2014、2016三年,其余年份均达90%以上。结论2011-2020年间广西各市、县参加梅毒血清学检测室间质评的医疗单位逐渐增加,开展项目及设备日趋完善,实验室的梅毒血清学检测各年合格率逐年上升,提示了广西地区医疗单位梅毒血清学检测能力和检测质量10年来有了一定提高。Objective This study aims to evaluate the external quality assessment of serological testing for syphilis in medical institutions in Guangxi,with the purpose of enhancing the management and quality control of syphilis laboratories.Methods Five external quality assessment specimens were dispatched to all participating laboratories for detection of non-specific treponema pallidum antibody serological qualitative and quantitative tests,as well as specific treponema pallidum antibody serological test,and then the test results were collected.The number of participating institutions,instruments and equipments,and quality assessment were analyzed in each year from 2011 to 2020.Results From 2011 to 2020,the number of laboratories participating in external quality assessment in Guangxi rose from 48 to 406.The participating institutions had successively carried out non-specific and specific antibody serological tests for syphilis,and the instruments and equipments gradually improved.The qualification rate of external quality assessment increased annually(χ^(2)=64.50,P<0.01),surpassing 97%in the five years from 2016 to 2020.The coincidence rate of qualitative test for non-specific antibody serological tests for syphilis among participating institutions was notably high from 2011 to 2020.Except for the year of 2018(68.0%),all other years yielded coincidence rates over 90%.While the coincidence rate of quantitative test showed significant fluctuations during the 10 year period,with values of 79.2%,56.7%,74.0%,72.2%,58.6%,74.4%,90.1%,60.3%,89.8%,and 71.2%,respectively.The coincidence rates of the treponema pallidum antibody serological test were relatively stable and exceeded 90%in all years,except for 2013,2014,and 2016.Conclusions From 2011 to 2020,the number of institutions participating in the external quality assessment of syphilis serological test in various cities and counties in Guangxi increased gradually.In addition,syphilis serological testing methods and equipment underwent progressive improvements,and the qualifi

关 键 词：梅毒血清学检测 室间质评 

分 类 号：R377.1[医药卫生—病原生物学]