艾灸联合钙尔奇D治疗原发性骨质疏松的疗效评估  

Therapeutic Effect of Moxibustion in Combination with Caltrate D on Primary Osteoporosis

作　　者：李志更[1] 刘林 马培[3] 张宁[2] 周宇馨 刘阳[2] 岳利峰 卫景沛 康庆[2] LI Zhigeng;LIU Lin;MA Pei;ZHANG Ning;ZHOU Yuxin;LIU Yang;YUE Lifeng;WEI Jingpei;KANG Qing(Institute of Basic Theory for Traditional Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing 100700,China;Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences,Beijing 100193,China)

机构地区：[1]中国中医科学院基础理论研究所,北京100700 [2]北京中医药大学东直门医院,北京100700 [3]中国医学科学院药用植物研究所,北京100193

出　　处：《世界中医药》2023年第20期2959-2962,共4页World Chinese Medicine

基　　金：国家自然科学基金项目(81302960,82174046);北京中医药大学杰出青年人才项目和青年名医培育项目(BUCM-2019-JCRC007,BUCM-2019-QNMYB011);中国医学科学院医学与健康科技创新工程项目(2021-I2M-1-031)。

摘　　要：目的:评估艾灸联合钙尔奇D治疗原发性骨质疏松的疗效。方法:回顾性选取2016年9月至2019年9月期间诊疗的120例原发性骨质疏松的患者,将其随机分为对照组和艾灸组,对照组采用钙尔奇D治疗,艾灸组在同等剂量钙尔奇D治疗的基础上,增加艾灸治疗,治疗周期为6个月。对比2组治疗前后的疼痛积分(VAS)、骨密度(BMD)、25羟基维生素D3、Ⅰ型胶原交联C端肽(β-CTX)、甲状旁腺激素(PTH)指标变化和治疗有效率等方面进行疗效评估。结果:治疗后,与对照组比较,艾灸组能明显缓解骨质疏松症状、骨性疼痛,影像提示艾灸组更有效改善患者的BMD,骨代谢相关的3项指标均明显改善,各方面均有统计学意义(均P<0.01)。结论:艾灸联合钙尔奇D治疗原发性骨质疏松后,症状缓解,疗效提升,且未出现明显不良反应。Objective:To evaluate the therapeutic effect of moxibustion in combination with Caltrate D on primary osteoporosis.Methods:A total of 120 patients with primary osteoporosis treated from September 2016 to September 2019 were randomizd into a control group and a moxibustion group.The control group was treated with Caltrate D,and the moxibustion group with moxibustion in combination with Caltrate D.Both groups were treated for 6 months.The visual analogue scale(VAS) score,bone mineral density(BMD),25 hydroxy vitamin D3 [25(OH)D3],beta-C-terminal telopeptide(β-CTX),and parathyroid hormone(PTH) were determined before and after treatment,and the response rate was compared between the two groups.Results:Compared with the control group,moxibustion alleviated the symptoms and bone pain of osteoporosis.The moxibustion group outperformed the control group in improving the BMD and the 3 bone metabolism indicators(P<0.01).Conclusion:Moxibustion in combination with Caltrate D can relieve the symptoms and demonstrate improve effect on primary osteoporosis without causing obvious adverse reactions.

关 键 词：艾灸 钙尔奇D 原发性骨质疏松 疗效评估 

分 类 号：R245[医药卫生—针灸推拿学]