康复训练护理在替罗非班治疗急性脑梗死患者中的应用效果研究  

Study on effect of tirofiban in rehabilitation training nursing for patients with acute cerebral infarction

作　　者：李荣 李欣 辛均平 LI Rong;LI Xin;XIN Jun-ping(Department of Neurology,Wanzai County People's Hospital,Yichun 336100,China)

机构地区：[1]万载县人民医院神经内科,336100

出　　处：《中国现代药物应用》2023年第22期150-154,共5页Chinese Journal of Modern Drug Application

基　　金：宜春市科技计划项目(项目编号:2022ZDJH6286)。

摘　　要：目的观察康复训练护理在替罗非班治疗急性脑梗死患者中的应用效果。方法70例实施替罗非班治疗的急性脑梗死患者,随机分为研究组和对照组,每组35例。对照组采用常规护理,研究组在对照组基础上采用康复训练护理。比较两组护理前后生理应激指标[皮质醇(Cor)、肾上腺素(E)]、炎症因子指标[白细胞介素-6(IL-6)、C反应蛋白(CRP)]、生活质量、肢体运动能力、脑动脉血流动力学指标[阻力指数(RI)、搏动指数(PI)、平均血流速度(MFV)]及并发症发生情况、护理满意度。结果护理后,研究组Cor(241.47±21.41)nmol/L、E(68.26±4.45)ng/L、IL-6(94.36±4.44)ng/L、CRP(9.32±2.05)mg/L均低于对照组的(464.55±21.45)nmol/L、(85.53±4.43)ng/L、(105.06±4.45)ng/L、(12.18±2.03)mg/L,差异有统计学意义(P<0.05)。研究组并发症发生率5.71%低于对照组的22.86%,差异有统计学意义(P<0.05)。研究组护理满意度97.14%高于对照组的77.14%,差异有统计学意义(P<0.05)。护理后,两组Barthel指数(BI)评分均高于护理前,且研究组BI评分(70.73±2.32)分高于对照组的(65.22±2.33)分,差异有统计学意义(P<0.05)。护理后,两组Fugl-Meyer运动功能评定量表(FMA)评分均高于护理前,且研究组FMA评分(68.29±2.32)分高于对照组的(62.12±2.36)分,差异有统计学意义(P<0.05)。护理后,研究组RI(0.48±0.06)、PI(0.63±0.11)小于对照组的(0.54±0.07)、(0.74±0.10),MFV(75.15±7.79)cm/s大于对照组的(70.13±2.62)cm/s,差异有统计学意义(P<0.05)。结论在急性脑梗死患者实施替罗非班治疗过程中应用康复训练护理的效果显著优于常规护理,能够明显改善患者的生理应激、炎症因子指标及脑动脉血流动力学指标,提升生活质量及肢体运动能力,降低并发症发生几率,值得临床推广。Objective To observe the effect of tirofiban in rehabilitation training nursing for patients with acute cerebral infarction.Methods A total of 70 patients with acute cerebral infarction treated by tirofiban were randomly divided into a study group and a control group,with 35 cases in each group.The control group received conventional nursing,and the study group received rehabilitation training nursing based on the control group.Both groups were compared in terms of physiological stress indicators[cortisol(Cor),epinephrine(E)],inflammatory factor indicators[interleukin-6(IL-6),C-reactive protein(CRP)],quality of life,limb movement ability,cerebral hemodynamic indicators[resistance index(RI),pulsation index(PI),mean flow velocity(MFV)]before and after nursing,occurrence of complications and nursing satisfaction.Results After nursing,the study group had Cor of(241.47±21.41)nmol/L,E of(68.26±4.45)ng/L,IL-6 of(94.36±4.44)ng/L and CRP of(9.32±2.05)mg/L,which were lower than those of(464.55±21.45)nmol/L,(85.53±4.43)ng/L,(105.06±4.45)ng/L and(12.18±2.03)mg/L in the control group,and the differences were statistically significant(P<0.05).The complication rate of 5.71%in the study group was lower than that of 22.86%in the control group,and the difference was statistically significant(P<0.05).The nursing satisfaction of 97.14%in the study group was higher than that of 77.14%in the control group,and the difference was statistically significant(P<0.05).After nursing,Barthel index(BI)score in both groups was higher than that before nursing in this group,and BI score of(70.73±2.32)points in the study group was higher than that of(65.22±2.33)points in the control group.The differences were statistically significant(P<0.05).After nursing,Fugl-Meyer assessment scale(FMA)scores in both groups were higher than that before nursing in this group,and FMA score of(68.29±2.32)points in the study group was higher than that of(62.12±2.36)points in the control group.The differences were statistically significant(P<0.05).After nu

关 键 词：康复训练护理 急性脑梗死 替罗非班 脑动脉血流动力学 

分 类 号：R473.74[医药卫生—护理学]