MemTrax在线工具在社区老年糖尿病认知功能筛查中的应用价值  

The significance of MemTrax in screening mild cognitive impairment in elderly diabetes patients in community

作　　者：朱文奎[1] 刘炜[2] 徐群[3] 钱雅慧 俆绮 ZHU Wenkui;LIU Wei;XU Qun;QIAN Yahui;XU Qi(Department of Clinical Laboratory,Hudong Community Health Service Center of Shanghai Pudong New Area,Shanghai 200129,China;不详)

机构地区：[1]上海市浦东新区沪东社区卫生服务中心检验科,上海200129 [2]上海市浦东新区沪东社区卫生服务中心全科,上海200129 [3]上海市交通大学医学院附属仁济医院神经内科,上海200127

出　　处：《中华全科医学》2023年第12期2089-2092,共4页Chinese Journal of General Practice

基　　金：上海市浦东新区卫生健康委员会卫生计生科研项目(PW2021A-81);上海市自然科学基金项目(23ZR1439200)。

摘　　要：目的探讨运用在线记忆认知评估系统MemTrax(MTX)对社区老年糖尿病认知功能筛查的意义,为临床推广提供依据。方法于2022年9—10月选取上海市某社区家庭医生签约服务对象中纳入糖尿病慢病管理的老年糖尿病患者89例及非糖尿病患者62例为研究对象,收集所有研究对象的一般临床资料,同时采集静脉血检测空腹血糖(FPG)、血肌酐、血清尿素氮、尿酸、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、糖化血红蛋白,运用MTX在线工具测定正确率和反应时间。采用Spearman相关分析研究MTX正确率、反应时间与FPG、糖化血红蛋白、糖尿病病程的相关性,采用多因素logistic回归分析探究MTX正确率结果异常的影响因素。结果老年糖尿病组和对照组MTX正确率分别为78%(72%,82%)、82%(78%,88%)。Spearman相关分析显示,MTX正确率与FPG、糖化血红蛋白、糖尿病病程呈负相关关系,相关系数分别为-0.301、-0.393、-0.291。多因素logistic回归分析结果显示,年龄和糖尿病为MTX正确率异常的影响因素,OR值分别为0.902(95%CI为0.830~0.980)、3.523(95%CI为1.681~7.383)。结论糖尿病相关指标与MTX正确率密切相关,糖尿病为MTX正确率异常的影响因素,运用MTX正确率对社区老年糖尿病认知功能筛查有一定的价值。Objective To explore the relevance of using the MemTrax(MTX)online cognitive memory assessment system for screening diabetes in older people in the community,providing a basis for clinical promotion.Methods From September to October 2022,89 elderly diabetic patients and 62 non-diabetic patients,including the management of diabetic chronic diseases,were selected as research subjects from the service targets contracted by family doctors in a community in Shanghai,Collected general clinical data from all study subjects,At the same time,venous blood was collected for fasting plasma glucose(FPG),creatinine,serum urea nitrogen,uric acid,total cholesterol,triglyceride,high-density lipoprotein cholesterol,low-density lipoprotein cholesterol,glycosylated hemoglobin,and the MTX online tool was used to determine the correct rate and reaction time.Spearman correlation analysis was used to analyze the relationship between MTX accuracy,reaction time and FPG,glycosylated hemoglobin and diabetes outcome.Multifactor logistic regression analysis was used to explore the factors associated with abnormal MTX accuracy results.Results The correct rate of MTX was 78%(72%,82%)and 82%(78%,88%)in the elderly diabetes group and control group,respectively;Spearman correlation analysis showed that the correct rate of MTX was negatively correlated with FPG,glycosylated hemoglobin,and diabetes course,and the correlation coefficients were-0.301,-0.393,and-0.291,respectively.Multivariate logistic regression analysis showed that the OR values of age and diabetes as risk factors for abnormal MTX accuracy were 0.902(95%CI:0.830-0.980),3.523(95%CI:1.681-7.383).Conclusion Diabetes-related indicators are closely related to the accuracy of MTX,diabetes is a risk factor for abnormal accuracy of MTX,and the use of MTX accuracy has some value in community screening of elderly diabetes cognitive function.

关 键 词：老年糖尿病 MemTrax测试 认知功能障碍 上海市 Spearman相关分析 

分 类 号：R587.1[医药卫生—内分泌]