中药咳喘合剂对痰热壅肺证肺炎喘嗽患儿肺功能、免疫功能及血清炎症因子的影响  

Effects of traditional Chinese medicine Kechuan Mixture on lung function,immune function,and serum inflammatory factors in children with phlegm heat regulated lung syndrome and cough

作　　者：秦小刚[1] 张建玉[1] 陆文霞 QIN Xiaogang;ZHANG Jianyu;LU Wenxia(Department of Pediatrics,Wujin Hospital of Traditional Chinese Medicine,Jiangsu Province,Changzhou213100,China)

机构地区：[1]江苏省常州市武进中医医院儿科,江苏常州213100

出　　处：《中国医药导报》2023年第30期155-159,共5页China Medical Herald

基　　金：江苏省中医药科技发展项目(ZX2020B1)。

摘　　要：目的探究中药咳喘合剂对痰热壅肺证肺炎喘嗽患儿肺功能、免疫功能及血清炎症因子的影响。方法选取江苏省常州市武进中医医院儿科2019年10月至2022年10月收治的痰热壅肺证肺炎喘嗽患儿102例,采用随机数字表法将其分为对照组和研究组,各51例。对照组给予西药治疗,研究组在对照组的基础上给予中药咳喘合剂治疗。比较两组疗效,两组治疗前后肺功能、免疫功能及炎症因子水平。结果研究组疗效优于对照组(P<0.05)。治疗后,两组第一秒用力呼气容积/用力肺活量、呼气流量峰值水平高于治疗前,且研究组高于对照组(P<0.05)。治疗后,两组CD3^(+)、CD4^(+)/CD8^(+)高于治疗前,且研究组高于对照组(P<0.05)。治疗后,两组白细胞介素-8、降钙素原低于治疗前,且研究组低于对照组(P<0.05)。结论中药咳喘合剂可提升肺炎喘嗽痰热壅肺证患儿疗效,改善肺功能、免疫及炎症水平。Objective To explore the curative effect of traditional Chinese medicine Kechuan Mixture on lung function,immune function,and serum inflammatory factors in children with phlegm heat regulated lung syndrome and cough.Methods A total of 102 children with phlegm heat regulated lung syndrome and cough were selected from the Department of Pediatrics,Wujin Hospital of Traditional Chinese Medicine from October 2019 and October 2022,they were divided into control group and study group by random number table method,with 51 cases in each group.The control group was treated with western medicine,and the study group was treated with traditional Chinese medicine Kechuan Mixture on the basis of control group.The efficacy,lung function,immune function and inflammation level before and after treatment were compared between the two groups.Results The efficacy of the study group was better than that of the control group(P<0.05).After treatment,the forced expiratory volume in the one second/forced vital channel and peak expiratory flow of the two groups were higher than before treatment,and the study group was higher than the control group(P<0.05).After treatment,CD3^(+)and CD4^(+)/CD8^(+)in both groups were higher than before treatment,and the study group was higher than the control group(P<0.05).After treatment,interleukin-8 and procalcitonin in two groups were lower than before treatment,and the study group was lower than the control group(P<0.05).Conclusion The traditional Chinese medicine Kechuan Mixture can enhance the therapeutic effect of children with pneumonia,asthma,cough,phlegm heat accumulation in the lungs,and improve lung function,immunity,and inflammation levels.

关 键 词：小儿肺炎喘嗽 痰热壅肺证 咳喘合剂 

分 类 号：R272[医药卫生—中医儿科学]