出 处:《临床和实验医学杂志》2023年第21期2350-2352,F0003,共4页Journal of Clinical and Experimental Medicine
基 金:安徽省卫生健康适宜技术项目(编号:SYJS-201915)。
摘 要:目的分析单次竖脊肌平面阻滞(ESPB)与术中肋间神经阻滞(INB)分别联合患者静脉自控镇痛(PCIA)对胸腔镜肺叶切除术(VATS)患者术后恢复情况的影响。方法前瞻性选取2019年1月至2022年12月在宣城市中心医院接受VATS治疗的120例患者进行研究,按照随机数字表法将患者分为PCIA组、INB+PCIA组和ESPB+PCIA组,每组各40例。PCIA组给予单纯PCIA,INB+PCIA组给予INB联合PCIA,ESPB+PCIA组给予ESPB联合PCIA。分析3组患者术后1、6、12、24 h的疼痛程度,术后24 h镇痛相关指标(镇痛泵按压次数、输注总量)、肺功能[第1秒呼气容积(FEV1)、用量肺活量(FVC)、FEV1/FVC]、术后恢复相关指标(胸管拔除时间、首次下床时间、住院时间)和并发症。结果术后1、6、12、24 h,ESPB+PCIA组的视觉模拟评分法(VAS)评分均较INB+PCIA组、PCIA组低,INB+PCIA较PCIA组低,差异均有统计学意义(P<0.05)。术后24 h,ESPB+PCIA组的镇痛泵按压次数、输注总量均较INB+PCIA组、PCIA组少,INB+PCIA较PCIA组少,差异均有统计学意义(P<0.05)。术后24 h,ESPB+PCIA组的FEV1、FVC、FEV1/FVC水平均较INB+PCIA组、PCIA组高,INB+PCIA组较PCIA组高,差异均有统计学意义(P<0.05)。ESPB+PCIA组的胸管拔除时间、首次下床时间、住院时间均较INB+PCIA组、PCIA组短,INB+PCIA较PCIA组短,差异均有统计学意义(P<0.05)。INB+PCIA组、ESPB+PCIA组并发症发生率分别为7.50%、5.00%,均较PCIA组(25.00%)低,差异均有统计学意义(P<0.05)。结论ESPB和INB联合PCIA在VATS镇痛中均具有一定安全性,但前者对患者肺功能影响较小,能够更好地保障术后镇痛效果,有利于提升患者的术后早期恢复质量。Objective To analyze the effects of single erector spinae plane block(ESPB)and intraoperative intercostal nerve block(INB)combined with patient controlled intravenous analgesia(PCIA)on postoperative recovery quality in patients with video assisted thoracic surgery(VATS).Methods A prospective study was conducted on 120 patients who received VATS treatment at Xuancheng City Central Hospital from January 2019 to December 2022.The patients were divided into PCIA group,INB+PCIA group,and ESPB+PCIA group according to the random number table method,with 40 patients in each group.The PCIA group received pure PCIA,the INB+PCIA group received INB combined with PCIA,and the ESPB+PCIA group received ESPB combined with PCIA.The postoperative pain degree at 1,6,12 and 24 h after surgery,analgesia related indexes(number of analgesic pump presses and total infusion volume),lung function[forced expiratory volume in one second(FEV1),forced vital capacity(FVC),FEV1/FVC],postoperative recovery related indexes(chest tube removal time,first time out of bed,and hospitalization time)at 24 h after surgery and complications of the three groups were analyzed.Results The visual analogue scale(VAS)scores at 1,6,12 and 24 h after surgery in ESPB+PCIA group were lower than in INB+PCIA group and PCIA group,and those in the INB+PCIA group were lower than those in PCIA group,the differences were statistically significant(P<0.05).At 24 h after surgery,the number of analgesic pump presses and total infusion volume in the ESPB+PCIA group were lower than those in the INB+PCIA group and PCIA group,and those in the INB+PCIA group was lower than those in the PCIA group,the differences were statistically significant(P<0.05).At 24 h after surgery,the levels of FEV1,FVC,FEV1/FVC in ESPB+PCIA group were higher than those in INB+PCIA group and PCIA group,and those in the INB+PCIA group were higher than those in PCIA group,the differences were statistically significant(P<0.05).The chest tube removal time,first time out of bed,and hospitalization time of the E
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