丘脑室旁核在全身麻醉和睡眠觉醒神经通路中的作用  

Paraventricular thalamic nucleus nerve pathways involved in general anesthesia wakefulness and sleep wakefulness

作　　者：顾芸菲 陈苏衡 于恺华 鲍振星 李玉兰[2] GU Yunfei;CHEN Suheng;YU Kaihua;BAO Zhenxing;LI Yulan(The First Clinical Medical College of Lanzhou University,Lanzhou 730000,Gansu,China;Department of Anesthesiology,First Hospital of Lanzhou University,Lanzhou 730000,Gansu,China)

机构地区：[1]兰州大学第一临床医学院,甘肃兰州730000 [2]兰州大学第一医院麻醉科,甘肃兰州730000

出　　处：《中国临床药理学与治疗学》2023年第12期1436-1440,共5页Chinese Journal of Clinical Pharmacology and Therapeutics

基　　金：甘肃省卫生健康行业科研项目(GSWSKY2021-079)。

摘　　要：丘脑室旁核(paraventricular thalamic nucleus,PVT)是觉醒的关键核团。PVT在正常睡眠的觉醒调节中占据着重要作用,但在麻醉中其作用可能随着所处麻醉阶段的不同而不同。本文将围绕PVT觉醒功能神经通路来综述其在睡眠和麻醉中的作用。The paraventricular thalamic nucleus(PVT)is a key nucleus involved in wakefulness.PVT plays an important role in normal sleep-wake regu-lation,but its role may vary during anesthesia de-pending on the stage of anesthesia.This article will review the role of PVT in sleep and anesthesia based on its wakefulness function neural pathways.

关 键 词：丘脑室旁核 全身麻醉 睡眠 觉醒 意识 

分 类 号：R96[医药卫生—药理学] R614[医药卫生—药学]