MRI单次激发FSE序列评价胎儿脑沟发育的可行性  

Feasibility study on evaluation of fetal sulcus development by MRI with single shot fast spin echo sequence

作　　者：夏薇 周婧 郭豫 邵剑波[1] XIA Wei;ZHOU Jing;GUO Yu(Department of Imaging Center,Wuhan Children's Hospital(Wuhan Maternal and Child Healthcare Hospital),Tongji Medical College,Huazhong Universityof Science and Technology,Wuhan 430015,China)

机构地区：[1]华中科技大学同济医学院附属武汉儿童医院(武汉市妇幼保健院)影像中心,湖北武汉430015

出　　处：《放射学实践》2023年第12期1605-1610,共6页Radiologic Practice

基　　金：湖北省自然科学基金(2020CFB710);湖北省卫生计生科研基金(WJ2018H0160);武汉儿童医院科研基金(2020FE002);武汉儿童医院儿童影像医学研究室建设项目(2022FEYJS002);武汉市儿童影像医学临床医学研究中心建设项目(WSTB2022-38)。

摘　　要：目的:探讨MRI单次激发FSE序列评价宫内胎儿脑沟发育的可行性。方法:分析203例22~38孕周健康胎儿的脑部MRI图像,根据孕周分为17组,每一孕周为一组,评价胎儿半球间裂、外侧裂、顶枕沟、海马裂、胼胝体沟、距状裂、扣带沟、边缘沟、侧副沟、中央沟、额上沟、中央前沟、中央后沟、顶内沟、颞上沟、额下沟、颞下沟、枕颞沟、次级扣带沟、次级枕沟及岛沟是否可显示,并计算各孕周组中各个脑沟的可见率。结果:建立了22~38孕周胎儿大脑所有初级脑沟和部分次级脑沟的可见百分率的时间表。超过75%的胎儿在22孕周时可见半球间裂、外侧裂、顶枕沟、海马裂、胼胝体沟和距状裂;在24孕周可见扣带沟;在25孕周可见边缘沟、侧副沟、中央沟和额上沟;在26孕周可见中央前沟、中央后沟和顶内沟;在27孕周可见颞上沟和额下沟;在31孕周可见颞下沟、枕颞沟和次级扣带沟;在32孕周可见次级枕沟;在34孕周可见岛沟。结论:MRI单次激发FSE序列可用于评估胎儿脑沟的发育情况,可为评价胎儿脑部发育提供一定的参考标准,从而可辅助诊断脑发育滞后。Objective:To evaluate the development of fetal sulcus in uterus by MRI with single shot fast spin echo sequence.Methods:The MRI images of the brain of 203 normal fetuses at 22~38 weeks of gestation(17 groups in total)were retrospectively analyzed to evaluate the percentage of each fetal sulcus visibility according to gestational age by weeks,including interhemispheric fissure,lateral sulcus,parieto-occipital fissure,hippocampal fissure,callosal sulcus,calcarine fissure,cingular sulcus,marginal sulcus,collateral sulcus,central sulcus,superior frontal sulcus,precentral sulcus,postcentral sulcus,intraparietal sulcus,superior temporal sulcus,inferior frontal sulcus,inferior temporal sulcus,occipitotemporal sulcus,secondary cingular sulci,secondary occipital sulci and insular sulci.Results:A timeline was established for the percentage of all fetal cerebral primary sulcus and some se-condary sulcus visibility at 22~38 weeks of gestation.In over 75%of fetuses,interhemispheric fissure,lateral sulcus,parieto-occipital fissure,hippocampal fissure,callosal sulcus and calcarine fissure could be seen at 22 gestational weeks,cingular sulcus could be seen at 24 weeks,marginal sulcus,collateral sulcus,central sulcus and superior frontal sulcus could be seen at 25 weeks,precentral sulcus,postcentral sulcus and intraparietal sulcus could be seen at 26 weeks,superior temporal sulcus and inferior frontal sulcus could be seen at 27 weeks,inferior temporal sulcus,occipitotemporal sulcus and secondary cingular sulci could be seen at 31 weeks,secondary occipital sulci could be seen at 32 weeks,insular sulci could be seen at 34 weeks.Conclusion:The development of fetal sulcus could be evaluated by FSE sequence MRI,a reference standard for the fetal brain development has been suggested,which can be used to assist the diagnosis of brain development retardation.

关 键 词：胎儿 脑沟 脑组织发育 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R715.5[医药卫生—诊断学]