盐酸羟考酮复合丙泊酚麻醉用于老年患者内窥镜逆行胰胆管造影术的效果  

Effect of oxycodone hydrochloride combined with propofol anesthesia on endoscopic retrograde cholangiopancreatography in elderly patients

作　　者：赵秀娥 张娜娜 ZHAO Xiu'e;ZHANG Nana(Anesthesiology Department,the People's Hospital of Jiawang District of Xuzhou City,Xuzhou 221011;Electrical Shock Room,Xuzhou Oriental People's Hospital,Xuzhou 221000,China)

机构地区：[1]徐州市贾汪区人民医院麻醉科,江苏徐州221011 [2]徐州市东方人民医院电休克室,江苏徐州221000

出　　处：《临床医学研究与实践》2023年第36期74-77,共4页Clinical Research and Practice

摘　　要：目的探讨盐酸羟考酮复合丙泊酚麻醉用于老年患者内窥镜逆行胰胆管造影术(ERCP)的效果。方法选择2018年1月至2022年5月收治的90例行ERCP治疗的老年患者为研究对象,按照随机数字表法将其分为对照组和观察组,各45例。对照组给予舒芬太尼复合丙泊酚麻醉,观察组给予盐酸羟考酮复合丙泊酚麻醉。比较两组的麻醉效果。结果麻醉诱导后5 min(T_(1))、内镜达到咽部时(T_(2))、内镜进入胆管操作时(T_(3))、退镜时(T_(4)),观察组的收缩期血压(SBP)、舒张期血压(DBP)、心率(HR)均高于对照组,差异具有统计学意义(P<0.05)。观察组的术后苏醒时间短于对照组,丙泊酚用量少于对照组,差异具有统计学意义(P<0.05)。观察组的不良反应总发生率低于对照组,差异具有统计学意义(P<0.05)。结论盐酸羟考酮复合丙泊酚麻醉用于老年患者ERCP效果显著,可使患者血流动力学指标水平保持相对平稳状态,减少丙泊酚用量,缩短术后苏醒时间,降低不良反应总发生率,值得推广应用。Objective To investigate the effect of oxycodone hydrochloride combined with propofol anesthesia on endoscopic retrograde cholangiopancreatography(ERCP)in elderly patients.Methods A total of 90 elderly patients who underwent ERCP treatment from January 2018 to May 2022 were selected as the research objects,and the patients were divided into control group and observation group according to the random number table method,with 45 cases in each group.The control group was given sufentanil combined with propofol anesthesia,and the observation group was given oxycodone hydrochloride combined with propofol anesthesia.The anesthetic effects of the two groups were compared.Results At 5 min after anesthesia induction(T_(1)),when the endoscope reached the pharynx(T_(2)),when the endoscope entered the bile duct operation(T_(3))and when the endoscope was withdrawn(T_(4)),the systolic blood pressure(SBP),diastolic blood pressure(DBP)and heart rate(HR)in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The postoperative wake-up time of the observation group was shorter than that of the control group,the dosage of propofol was less than that of the control group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Oxycodone hydrochloride combined with propofol anesthesia has a significant effect on ERCP in elderly patients,it can keep the hemodynamic indexes levels of patients in a relatively stable state,reduce the dosage of propofol,shorten the postoperative wake-up time,and reduce the total incidence of adverse reactions,which is worthy of popularization and application.

关 键 词：盐酸羟考酮 丙泊酚 麻醉 内窥镜逆行胰胆管造影术 血流动力学 

分 类 号：R614[医药卫生—麻醉学]