比索洛尔联合胺碘酮对顽固性室性心律失常患者症状改善及不良反应的影响  

Impact of Bisoprolol Combined with Amiodarone on Symptom Improvement and Adverse Reactions of Patients with Refractory Ventricular Arrhythmia

作　　者：韩彩萍[1] 冉华中[1] HAN Caiping;RAN Huazhong(2^(rd)Department of Cardiovascular Medicine,Zhoukou Central Hospital,Zhoukou 466000,China)

机构地区：[1]周口市中心医院心血管内二科,河南周口466000

出　　处：《临床医学工程》2023年第12期1679-1680,共2页Clinical Medicine & Engineering

摘　　要：目的探讨比索洛尔联合胺碘酮对顽固性室性心律失常患者症状改善及不良反应的影响。方法100例顽固性室性心律失常患者随机分为两组各50例。对照组采用胺碘酮治疗,观察组采用比索洛尔联合胺碘酮治疗。比较两组的治疗效果、心电图指标以及不良反应。结果观察组的治疗总有效率为98.0%,高于对照组的86.0%(P<0.05)。治疗后,观察组的室性前期收缩数、短阵室速数均少于对照组(P<0.05)。观察组的药物不良反应发生率为8.0%,低于对照组的24.0%(P<0.05)。结论比索洛尔联合胺碘酮治疗顽固性室性心律失常能够显著改善患者的心功能,提高治疗效果,减少药物不良反应。Objective To explore the impact of bisoprolol combined with amiodarone on symptom improvement and adverse reactions of patients with refractory ventricular arrhythmia.Methods 100 patients with refractory ventricular arrhythmia were randomly divided into two groups,with 50 cases in each group.The control group was treated with amiodarone,and the observation group was treated with bisoprolol combined with amiodarone.The therapeutic effects,electrocardiogram indicators and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 98.0%,higher than 86.0%in the control group(P<0.05).After treatment,the number of premature ventricular contractions and the number of short ventricular tachycardia in the observation group were less than those in the control group(P<0.05).The incidence of adverse drug reactions in the observation group was 8.0%,lower than 24.0%in the control group(P<0.05).Conclusions Bisoprolol combined with amiodarone in the treatment of refractory ventricular arrhythmia can significantly improve the cardiac function of patients,improve the therapeutic effect and reduce adverse drug reactions.

关 键 词：比索洛尔 胺碘酮 顽固性室性心律失常 治疗效果 不良反应 

分 类 号：R541.7[医药卫生—心血管疾病]