医用多孔钛合金表面改性技术研究进展  

Research progress of surface modification techniques of porous titanium alloy for medical use

作　　者：王柄皓 杨成亮 吕玉廷 王立强[5] WANG Binghao;YANG Chengliang;LYU Yuting;WANG Liqiang(Guangxi Zhuang Autonomous Region Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases,Baise Guangxi 533000,China;Guangxi Key Laboratory of Basic Research and Translation of Bone and Joint Degenerative Diseases,Baise Guangxi 533000,China;Affiliated Hospital of Youjiang Medical University of Nationalities,Baise Guangxi 533000,China;Shandong University of Science and Technology,School of Mechanical and Electronic Engineering,Qingdao Shandong 266400,China;Shanghai Jiaotong University,State Key Laboratory of Metal Matrix Composites,Shanghai 201100,China)

机构地区：[1]广西壮族自治区骨与关节退行性疾病生物医用材料工程研究中心,广西百色533000 [2]广西骨与关节退行性疾病基础研究与转化重点实验室,广西百色533000 [3]右江民族医学院附属医院,广西百色533000 [4]山东科技大学机械电子工程学院,山东青岛266400 [5]上海交通大学金属基复合材料国家重点实验室,上海201100

出　　处：《有色金属材料与工程》2023年第6期10-17,51,共9页Nonferrous Metal Materials and Engineering

基　　金：国家自然科学基金资助项目(82071361和32160209)。

摘　　要：多孔钛合金拥有良好的力学性能,能够降低“应力屏蔽”效应,促进与组织的结合,但其功能化方面还存在不足。表面改性能够通过改造材料表面形貌或在材料表面负载功能成分等形式,赋予材料良好的成骨、抗菌及耐腐蚀、耐磨性等功能特性。区别于钛板/棒等致密钛材,多孔钛具有复杂的内部结构,因而,其改性多在流体(液体、气体)介质中进行以实现良好的包覆性。按照表面改性原理及作用成分性质分类,重点介绍了传统与新型医用多孔钛合金表面改性方法及效果,总结分析了不同方法间的优缺点及影响因素等,以期为医用多孔钛合金表面改性提供指导。Porous titanium alloys have good mechanical properties,which can reduce the"stress shielding"effect and promote the bonding with biological tissues,but there are still deficiencies in their functionalization.Surface modification can be achieved by modifying the surface morphology of the material or loading functional components on the material surface,thereby imparting good functional properties such as osteoblastic,antimicrobial and corrosion/abrasion resistance.Unlike dense titanium materials such as titanium plates/bars,porous titanium has a complex internal structure,and thus its modification is mostly carried out in fluid(liquid,gas)media to achieve good cladding properties.This paper is categorized according to the principle of surface modification and the nature of the functional components,focusing on surface modification methods and effects of the traditional and new medical porous titanium alloys,and the advantages,disadvantages and influencing factors of different methods are summarized and analyzed,aiming to provide guidance for the surface modification of medical porous titanium alloys.

关 键 词：医用植入物 多孔钛合金 表面改性 生物性能 

分 类 号：TG146[一般工业技术—材料科学与工程]