无机金属异质结半导体在肿瘤治疗中的应用研究  

Application of inorganic metal heterojunction semiconductors in cancer therapy

作　　者：贺宗炎 缪煜清[1] 李钰皓 HE Zongyan;MIAO Yuqing;LI Yuhao(School of Materials and Chemistry,University of Shanghai for Science and Technology,Shanghai 200093,China)

机构地区：[1]上海理工大学材料与化学学院,上海200093

出　　处：《有色金属材料与工程》2023年第6期43-51,共9页Nonferrous Metal Materials and Engineering

基　　金：上海市自然科学基金资助项目(19ZR1434700)。

摘　　要：随着对半导体催化机制的不断研究,发现半导体材料在光/声刺激下会发生催化反应,从而产生活性氧。因此,近年来半导体材料被广泛研究用于肿瘤治疗。基于不同激发源,用半导体材料催化治疗主要分为光催化治疗和声催化治疗,其中异质结半导体材料与单纯的半导体材料相比,因其特殊的电子转移方式,在肿瘤催化治疗中表现出更好的疗效。通过分析异质结材料的催化机制,将近年来设计合成的多种无机金属异质结分为4类,同时详细讨论了不同异质结材料在光/声催化治疗领域的研究和发展。希望从异质结催化增强的机制出发,为用于高效肿瘤治疗无机金属异质结材料的设计提供新的思路。With a continuous study on the catalytic mechanism of semiconductors,it has been found that semiconductor materials can undergo catalytic reactions to produce reactive oxygen species under light/ultrasound stimulation.Therefore,it has been widely studied and applied to tumor treatment in recent years.Based on different excitation sources,semiconductor catalytic therapy can be mainly divided into photocatalytic therapy and sonocatalytic therapy.Heterojunctions exhibit better efficacy in tumor catalytic therapy due to their unique electron transfer methods compared to pure semiconductor materials.By analyzing the catalytic mechanism of heterojunction materials,this review classifies variously synthesized inorganic metal heterojunctions in recent years into four categories.Meanwhile,the research and development of different heterojunction materials in the field of photocatalytic and sonocatalytic therapy are discussed in detail.It is hoped to provide a new idea to design inorganic metal heterojunction materials for efficient tumor therapy based on the mechanism of catalytic enhancement of heterojunctions.

关 键 词：半导体 异质结 光催化治疗 声催化治疗 

分 类 号：TG146.1[一般工业技术—材料科学与工程]