新型生物可吸收支架冠脉介入治疗急性心梗的有效性及安全性分析  

Effectiveness and Safety Analysis of Coronary Intervention with Novel Bioabsorbable Stents in Treatment of Acute Myocardial Infarction

作　　者：姜海瑞[1] 金翎羽 马晓欧[1] 梁波[1] JIANG Hairui;JIN Lingyu;MA Xiaoou;LIANG Bo(Department of Cardiology,Qiqihar Medical University the Second Affiliated Hospital,Qiqihar,Heilongjiang 161000)

机构地区：[1]齐齐哈尔医学院附属第二医院心内科,黑龙江齐齐哈尔161000

出　　处：《智慧健康》2023年第22期187-191,共5页Smart Healthcare

基　　金：黑龙江省卫生健康委科研课题《Neovas在医院急救体系下临床应用》(项目编号:20210303010373)。

摘　　要：目的探讨新型生物可吸收支架冠脉介入治疗急性心梗的有效性与安全性。方法选取2020年9月—2022年4月于齐齐哈尔医学院附属第二医院接受冠脉介入治疗的214例符合标准的急性心梗患者,依据介入方案不同分为两组。实验组107例,使用NeoVas生物可吸收支架;对照组107例,使用PARTNER永久涂层支架。患者术后均接受不少于1年的随访以及冠脉造影复查,回顾性调研两组临床资料,观察两组介入治疗成功率、晚期血管丢失(LLL)情况、支架节段再狭窄与支边血管开口情况,记录两组抗血小板药物使用率与主要心血管不良事件(MACE)发生情况,统计无MACE生存率。结果两组冠脉介入治疗成功率均为100%,术后管腔狭窄残余差异无统计学意义(P>0.05)。术后1年,实验组LLL、支架再狭窄率、支边血管开口变化、阿司匹林使用率、双联抗血小板率同对照组比较差异无统计学意义(P>0.05)。实验组各MACE发生率与无MACE生存率同对照组比较差异无统计学意义(P>0.05)。结论新型生物可吸收支架冠脉介入治疗急性心梗的成功率高,MACE发生率低,可以获得与传统永久涂层支架相似的疗效与安全性,值得临床应用推广。Objective:To explore effectiveness and safety of coronary intervention with novel bioabsorbable stents in treatment of acute myocardial infarction.Methods The paper chose 214 patients with acute myocardial infarction with coronary intervention treatment in Qiqihar Medical University the Second Affiliated Hospital from September 2020 to April 2022,and divided them into two groups based on different intervention schemes.107 cases in experimental group were treated with NeoVas bioabsorbable stents,107 cases in control group with PARTNER permanently coated stents.With follow-up and coronary angiography review for at least one year after surgery,the paper reviewed and researched clinical data of two groups to observe success rate of interventional treatment,late stage vascular loss(LLL),stent segment restenosis,and branch vessel opening,recorded use rate of antiplatelet drugs and incidence of major cardiovascular adverse events(MACE)of two groups,statistically analyzed survival rate without MACE.Results Success rate of coronary intervention treatment of two groups was 100%,there was no statistically significant difference in residual stenosis after surgery(P>0.05).One year after surgery,there was no statistically significant difference in LLL,stent restenosis rate,changes in branch vessel opening,aspirin usage rate,and dual antiplatelet rate between experimental group and control group(P>0.05).There was no statistically significant difference in incidence of MACE and survival rate without MACE between experimental group and control group(P>0.05).Conclusion Novel bioabsorbable stent can achieve high success rate in treatment of acute myocardial infarction through coronary intervention,with low incidence of MACE,and similar effect and safety as traditional permanent coated stents,which is worthy of clinical application and promotion.

关 键 词：急性心梗 冠脉介入治疗 新型生物可吸收支架 疗效 安全性 

分 类 号：R542.22[医药卫生—心血管疾病]