基于蒙特卡罗的脑血氧检测光源——探测器最优距离研究  

Study on the Optimal Distance of Light Source-Detector for Cerebral Blood Oxygen Detection Based on Monte Carlo

作　　者：曹焱 邢志明 赵斌 董祥美[1] 史以珏[2] 高秀敏[1] CAO Yan;XING Zhiming;ZHAO Bin;DONG Xiangmei;SHI Yijue;GAO Xiumin(School of Optical-electrical and Computer Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China;Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China)

机构地区：[1]上海理工大学光电信息与计算机工程学院,上海200093 [2]上海交通大学医学院附属瑞金医院,上海200025

出　　处：《软件导刊》2023年第12期117-123,共7页Software Guide

基　　金：国家重点研发计划项目(2018YFC1313803)。

摘　　要：为提高近红外光谱技术的脑血氧检测装置测量精度,需要选择最优的光源—探测器(SD)距离。传统的脑血氧检测装置,其传感器探头部分的SD距离是固定的,且在选择SD距离时没有经过研究,多根据经验进行选择,因而会造成实际使用中测量结果的不准确。根据光在头部组织中的传输特性,选定一组颅脑组织的特性参数,利用蒙特卡罗方法对5层颅脑组织模型进行仿真,研究光在头部组织中的传输特性,根据光子传输路径分析光子在组织中传输的最大可达深度和散射传输距离。通过分析有效深度比(EDR)和灰质层信息比(GMLIR),选择出适合此组选定颅脑参数的一组最优距离SD=1cm和SD=3.5cm。与传统检测装置相比,通过优化光源—探测器之间的距离,为脑血氧检测装置的传感器设计及装置测量精度优化提供了一个新思路。To improve the measurement accuracy of cerebral oximetry devices using near-infrared spectroscopy,it is necessary to select the optimal source-detector(SD)distance.Conventional cerebral oximetry devices with a fixed SD distance for the sensor probe part are mostly se⁃lected based on experience and without specific theoretical studies,which can cause inaccurate measurement results in actual use.According to the transmission characteristics of light in the head tissue,a set of characteristic parameters of cranial tissues is selected,and the five-layer cranial brain tissue model is simulated using Monte Carlo method to study the transmission characteristics of light in the head tissue,and the maximum reachable depth and scattered transmission distance of photon transmission in the tissue are analyzed according to the transmission path of photons.By analyzing the effective depth ratio(EDR)and gray matter layer information ratio(GMLIR),a set of optimal distances SD=1 cm and SD=3.5 cm are selected to fit this group of selected cranial parameters.Compared with the traditional detection device,by optimizing the distance between the light source-detector,it will provide a new idea for the sensor design of the cerebral blood oxygen detection device and the measurement accuracy improvement of the device.

关 键 词：脑血氧检测 光源—探测器距离 传感器 蒙特卡罗方法 组织模型 

分 类 号：TH776[机械工程—仪器科学与技术] R318[机械工程—精密仪器及机械]