痰液标本结核分枝杆菌与支气管肺泡灌洗液标本结核分枝杆菌培养结果比较  

Comparison of Mycobacterium tuberculosis culture results between sputum specimens and bronchoalveolar lavage fluid specimens

作　　者：邬俊勇 黄韬 江光荣 WU Junyong;HUANG Tao;JIANG Guangrong(Department of Laboratory,Yichun People's Hospital,Yichun,Jiangxi,336028,China)

机构地区：[1]宜春市人民医院检验科,江西宜春336028

出　　处：《当代医学》2023年第31期120-123,共4页Contemporary Medicine

摘　　要：目的分析痰液标本结核分枝杆菌、支气管肺泡灌洗液标本结核分枝杆菌培养结果。方法选取2020年1月至2021年6月宜春市人民医院收治的100例疑似肺结核患者作为研究对象,均接受痰液培养、支气管肺泡灌洗液培养,以临床综合诊断为金标准,比较两种结核分枝杆菌培养方法培养结果及诊断效能。结果支气管肺泡灌洗液培养结核分枝杆菌所需时间为(8.93±0.35)d,短于痰液培养的(23.98±2.44)d,差异有统计学意义(P<0.05)。100例疑似肺结核患者经临床综合诊断阳性91例,支气管肺泡灌洗液培养检出真阳性89例,痰液培养检出真阳性68例。支气管肺泡灌洗液培养结果对肺结核诊断的灵敏度、符合率均高于痰液培养,差异有统计学意义(P<0.05);两种检测方法特异度比较差异无统计学意义。结论支气管肺泡灌洗液培养诊断肺结核的灵敏度较高,有利于提高疑似肺结核患者疾病检出率,且该方法获得培养结果所需时间较短,值得临床推广应用。Objective To analyze the Mycobacterium tuberculosis culture results between sputum specimens and bronchoalveolar lavage fluid specimens.Methods 100 suspected pulmonary tuberculosis patients admitted to Yichun People's Hospital from January 2020 to June 2021 were se-lected as the research subjects.All of them received sputum specimens and bronchoalveolar lavage fluid specimens,with clinical comprehensive diag-nosis as the gold standard,the culture results and diagnostic efficiency of the two methods were compared.Results The time required for the culture of Mycobacterium tuberculosis in bronchoalveolar lavage fluid specimens was(8.93±0.35)d,which was shorter than(23.98±2.44)d in sputum speci-mens,and the difference was statistically significant(P<0.05).Among 100 suspected pulmonary tuberculosis patients,91 cases were clinically posi-tive,89 cases were true positive by bronchoalveolar lavage fluid specimens,and 68 cases were true positive by sputum specimens.The sensitivity and coincidence rate of bronchoalveolar lavage fluid specimens were higher than those of sputum specimens,the differences were statistically signifi-cant(P<0.05),and there was no statistically significant difference in specificity between the two methods.Conclusion Bronchoalveolar lavage flu-id specimens has high sensitivity in the diagnosis of pulmonary tuberculosis,which is conducive to improving the detection rate of suspected pulmo-nary tuberculosis patients,and the method requires a shorter time to obtain the culture results,which is worthy of clinical promotion and application.

关 键 词：肺结核 结核分枝杆菌 痰涂片 支气管肺泡灌洗液 致病菌培养 

分 类 号：R52[医药卫生—内科学]